Modification of cutaneous reflexes during visually guided walking

Abstract

Although it has become apparent that cutaneous reflexes can be adjusted based on the phase and context of the locomotor task, it is not clear to what extent these reflexes are regulated when locomotion is modified under visual guidance. To address this, we compared the amplitude of cutaneous reflexes while subjects performed walking tasks that required precise foot placement. In one experiment, subjects walked overground and across a horizontal ladder with narrow raised rungs. In another experiment, subjects walked and stepped onto a series of flat targets, which required different levels of precision (large vs. narrow targets). The superficial peroneal or tibial nerve was electrically stimulated in multiple phases of the gait cycle in each condition and experiment. Reflexes between 50 and 120 ms poststimulation were sorted into 10 equal phase bins, and the amplitudes were then averaged. In each experiment, differences in cutaneous reflexes between conditions occurred predominantly during swing phase when preparation for precise foot placement was necessary. For instance, large excitatory cutaneous reflexes in ipsilateral tibialis anterior were present in the ladder condition and when stepping on narrow targets compared with inhibitory responses in the other conditions, regardless of the nerve stimulated. In the ladder experiments, additional effects of walking condition were evident during stance phase when subjects had to balance on the narrow ladder rungs and may be related to threat and/or the unstable foot-surface interaction. Taken together, these results suggest that cutaneous reflexes are modified when visual feedback regarding the terrain is critical for successful walking.

We Are Upright-Walking Cats: Human Limbs as Sensory Antennae During Locomotion

“…Both task-and phase-dependent modulation of afferent feedback during locomotion is mediated by premotoneuronal gating via spinal CPGs (13,47,87). Task-dependent modulation of cutaneous reflexes has been studied between standing and walking (40), running (17), and hopping (28); level walking, incline walking, and stair climbing (42); and walking under different visual feedback conditions (69), at various frequencies of contralateral arm movements (83) and between static and rhythmic contractions (5,70,91), indicating that static and rhythmic movements have differential neural control mechanisms (87). Such mechanisms also mediate phase-dependent changes in sensory feedback during rhythmic output.…”