Models of intracranial aneurysms for angiographic imaging modalities. A technical note

Žurauskas, Edvardas; Ušinskienė, Jurgita; Gaigalaitė, Virginija; Blanc, Raphaël; Usinskas, Andrius; Laurinavičius, Arvydas

doi:10.3390/medicina43070071

Cited by 1 publication

(1 citation statement)

References 9 publications

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“…From clinical practice, it is known that specific sites in the human circulatory system are particularly sensitive to the development of cardiovascular diseases 2 . Local hemodynamics is crucial to understand the development and the complications derived from medical conditions like atherosclerosis 3,4 , aneurysms [5][6][7][8] and stenoses [9][10][11] . Some medical interventions, such as stent implantation and bypasses, can disturb regular hemodynamics [12][13][14] and their impact on fluid flow must be understood.…”

Section: Introductionmentioning

confidence: 99%

Fabrication of 3d Mili-Scale Channels for Hemodynamic Studies

Doutel

Carneiro

Oliveira

et al. 2015

J. Mech. Med. Biol.

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3D mili-scale channel representing simplified anatomical models of blood vessels were constructed in polidimethylsiloxane (PDMS). The objective was to obtain a sequential method to fabricate transparent PDMS models from a mold produced by rapid prototyping. For this purpose, two types of casting methods were compared, a known lost-wax casting method and a casting method using sucrose. The channels fabricated by both casting methods were analyzed by Optical Microscopy, Scanning Electron Microscopy (SEM), and Energy Dispersive X-ray Spectroscopy (EDS). The lost-wax method is not ideal since the channels become contaminated during the removal process. The models produced with the lost-sucrose casting method exhibit much better optical characteristics. These models are transparent with no visible contamination, since the removing process is done by dissolution at room temperature rather than melting. They allow for good optical access for flow visualization and measurement of the velocity field by micro-Particle Image Velocimetry (μPIV). The channels fabricated by the lost-sucrose casting method were shown to be suitable for future hemodynamic studies using optical techniques.

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