Humankind faces many problems such as like terrorism, crime, the collapse of the family unit, drug abuse, war, theft, etc., the multidisciplinary research was done to find whether that there are basic and common psychological reasons are or not. So, I have found some fundamental factors that are significantly limited or revers of the human intelligence by some decisions making and those limitations might be due to activating of delusional thoughts and decisions which are declined of intelligence, mainly cause by psychological mind viruses[ MV] in them, as I hypothesis, here. Those issues are been impact on optimal living, psychological, physical and social well-being. So, better practical solutions and preventive methods are needed. The leading psychological limiting factors for intelligence development are known as MV and its' remedies are healthy mind viruses [HMV]. The intelligent learning, training (meditation) and intelligent decisions might evolve the nature of the brain, nurture and x-micro particle genome [X-MPG], all these six factors seem to be interdepended. The X-MPG might bond with the xunique micro-particle [X-UMP]. However, the X-UMP might never evolve or change and it might maintain the uniqueness of the conscious state of a person. But, the X-MPG helps to evolve the latent potential level of well-being and optimal living gradually, of the related 4 person. Here, I show the unearthed-core of early Buddhist teachings, training (meditation) and decisions inclusive of the 8-fold path may be an efficient methodology for Intelligence evolution. The evolution of nature, nurture, X-MPG, psychological well-being, and intelligence might be represented in a theoretical 3D graph. If life after death occurs, when clinical death of a person's finally evolved level and micro quantum key of the X-MPG[ +X-UMP] might be crucial to natural transmission to bond with a matching and vacant zygote/early embryo of its micro quantum particles and its new conscious state, might depend on the lastly evolved genome of the X-MPG. However there are many more mysterious issues to be solved in future researches, so this might not a theory of everything on the main theme.