2006
DOI: 10.1590/s0102-86502006000100009
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Modelo experimental do carcinossarcoma 256 de Walker em bexiga de ratos

Abstract: RESUMO ABSTRACTPurpose: An animal model to study bladder tumor with Walker 256. Methods: Bladders rats Wistar was catheterized via urethra and compression lesion of the wall bladder was realized with a little clamping after laparotomy. One total of the 0,3 ml suspension with 3 x 10 5 cels viable of the carcinossarcoma was instilled into each bladder. The animals were sacrificed after eight and 13 days. Results: The index of tumor incidence was 100% and the average of surviving was 14,5 days. Conclusion: The mo… Show more

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Cited by 4 publications
(1 citation statement)
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“…Without previous acid acetic inoculation the lesion is inconsistent and uneven, with tumor growth on few rats. That agrees with Oliveira et al 7 fi ndings where the inoculation on gastric mucosa was only made possible with a previous lesion and Dornelas et al 10 fi ndings where tumor implantation happened only on the spot where the bladder was injured, demonstrating that unharmed mucosa does not allow tumor implantation. On both groups B and C the tumor implantation rate was 100%, without difference between concentrations, similar to other inoculation Walker 256 carcinoma models, like kidney, 9 bladder, 10 stomach, 7 mouth 11 and others.…”
Section: Discussionsupporting
confidence: 86%
“…Without previous acid acetic inoculation the lesion is inconsistent and uneven, with tumor growth on few rats. That agrees with Oliveira et al 7 fi ndings where the inoculation on gastric mucosa was only made possible with a previous lesion and Dornelas et al 10 fi ndings where tumor implantation happened only on the spot where the bladder was injured, demonstrating that unharmed mucosa does not allow tumor implantation. On both groups B and C the tumor implantation rate was 100%, without difference between concentrations, similar to other inoculation Walker 256 carcinoma models, like kidney, 9 bladder, 10 stomach, 7 mouth 11 and others.…”
Section: Discussionsupporting
confidence: 86%