Modelo experimental de vasectomia laparoscópica em ratos

Abstract

OBJETIVO: Descrever um modelo experimental de vasectomia laparoscópica em ratos. MÉTODOS: Foram utilizados 35 ratos Rattus norvegicus albinus da linhagem Wistar. Após a anestesia, os ratos foram submetidos ao pneumoperitôneo através da agulha de Veress com PCO2 de 7mmHg. Depois, foram transpassados pela parede abdominal um trocater de 11mm de espessura e dois trocateres com 5 mm de espessura. Através destes foram introduzidos na cavidade abdominal à ótica (10mm) e as pinças utilizadas na dissecção, cauterização e secção do canal deferente e seus vasos. RESULTADOS: Durante o ato operatório dois animais (5,74%) apresentaram sangramento, contido com cauterização. Ocorreu um óbito na indução anestésica (2,85%) e outro (2,85%) no quarto dia pós-operatório de causa não identificada. Após 08 dias havia 33 ratos vivos (94,28%). CONCLUSÃO: Neste modelo, o material cirúrgico é o mesmo utilizado em humanos e são aplicados todos os procedimentos básicos da cirurgia laparoscópica, tornando-o factível para o treinamento de acadêmicos, médicos residentes e cirurgiões.

Invasive treatment to control neuropathic pain

“…Percutaneous neurosurgery under sedation is safer than open surgeries, in addition to allowing the physiological mapping of the desired target and simulation of postoperative situation. Neurolytic substances involve complications (less frequent, such as sympathectomies), being safer the use of physical media such as cold (criocoagulation) or the most commonly used due to further availability, heat (radiofrequency) to interrupt nervous pathways and centers 6,7,8,9 .…”

“…Neuropathic pain may be treated with neurosurgical methods, depending on the complexity and etiology of pain. In cancer patients, the indication of more invasive procedures for adequate pain control, including neuropathic pain, shall not be delayed, since this control leads to significant improvement in their QL, especially for those with advanced disease and reserved prognosis 8,9 . Neurosurgical technique shall be chosen as from the understanding of the pathophysiology and topography of neural structures involved with pain in the specific case.…”

“…More and more, procedures are enriched with neurophysiologic and neuroimaging data so as to decrease patients' participation time. Pathways may be interrupted with chemical injury with neurolytic agents, thermal of criocoagulation or thermocoagulation devices, ischemic by mechanical compression, and even actinic with the combina-tion of stereotactic and multicolimated radiotherapy methods [6][7][8][9] . Neuroradiological studies, from simple X-rays, computerized tomography radioscopy, and more recently MRI and ultrasound images, may be used in the pre, peri and postoperative periods of such procedures.…”