Modelling of multilayer biological medium under molecular communication paradigm

Abstract

Abstract-Molecular communication is an emerging paradigm that enables both the biological and synthetic nanomachines to communicate with each other within an aqueous biological environment such as the communication between living cells. Prediction of the number of drug molecules near a target site, e.g., tumor cells, is very important for determining the required drug dosages to increase positive therapeutic outcomes. In this paper, we derive an analytical expression for the received molecular signal in a multilayer biological environment. We also present development of particle-based simulator and the analytical results for threelayer biological medium compared well with the simulation results. The effect of the diffusion coefficient and the separation distance between the transmitter and the receiver (e.g., targeted cells) are examined.

Implantable Biosensor Interface Platform for Monitoring of Atherosclerosis

“…The inverse Laplace transform of the concentration expression given in Eq. ( 11) can be evaluated using Zakian's method as 9.2 in [19]. The number of the received PTX3 molecules by the biosensor is significantly affected by the concentration in the vicinity of the biosensor.…”