Modeling, simulation, and optimization of the centrifugal separation of a microalgae-culture medium mixture

Disconzi, Fernanda Perazzolo; Borghi, Fabrício T.

doi:10.1016/j.biombioe.2020.105871

Cited by 3 publications

(1 citation statement)

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“…Centrifugation is a separation process that allows the denser fraction to be sedimented and separated from the lighter liquid. It can be applied for nanoparticle separation, such as in microalgae harvesting [ 12 ], or nanomaterial purification [ 13 ]. Centrifugation is also commonly used for the concentration or dewatering process of finely dispersed particles in a liquid suspension phase [ 14 ].…”

Section: Introductionmentioning

confidence: 99%

Preparation of High-Solid Microfibrillated Cellulose from Gelidium amansii and Characterization of Its Physiochemical and Biological Properties

Kim

Istianah

et al. 2022

J. Microbiol. Biotechnol.

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Microfibrillated cellulose (MFC) is a valuable material with wide industrial applications, particularly for the food and cosmetics industries, owing to its excellent physiochemical properties. Here, we prepared high-solid microfibrillated cellulose (HMFC) from the centrifugation of Gelidium amansii -derived MFC right after fibrillation. Dispersion properties, morphology, and structural changes were monitored during processing. HMFC has a five-fold higher solid concentration than MFC without significant changes to dispersion properties. SEM images and FTIR spectra of HMFC revealed a stable surface and structure against centrifugal forces. HMFC exhibited 2,2′-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical scavenging activity, although it could not scavenge 2,2-diphenyl-1-picrylhydrazyl (DPPH). Moreover, HMFC inhibited the generation of LPS-induced excessive nitrite and radial oxygen species in murine macrophage RAW264.7 cells. Additionally, HMFC suppressed LPS-induced Keap-1 expression in the cytosol but did not alter iNOS expression. HMFC also attenuated the UVB-induced phosphorylation of p38, c-Jun N-terminal kinase (JNK) 1/2, and extracellular-signal-regulated kinase (ERK) 1/2, as well as the phosphorylation of c-Jun in the immortalized human skin keratinocyte HaCaT cells. Therefore, the application of centrifugation is suitable for producing high-solid MFC as a candidate material for anti-inflammatory and anti-oxidative marine cosmeceuticals.

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Section: Introductionmentioning

confidence: 99%