Modeling Requirements for Computer Simulation of Cerebral Aneurysm

Ghodsi, Seyed Roholah; Esfahanian, Vahid; Ghodsi, Seyed Mohammad

doi:10.1155/2014/653845

Cited by 5 publications

(2 citation statements)

References 48 publications

(56 reference statements)

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“…12 To account for fluid-structure-interaction simulation, additional vessel wall information is required (e.g., local wall thickness, material model, and parameters). 29,35 However, realistic values are difficult to acquire and few studies have managed the first assessments. 13,57 Overall, it is important to emphasize that vessel wall modeling only adds knowledge if precise wall information exists.…”

Section: Vessel Wall Conditionsmentioning

confidence: 99%

A review on the reliability of hemodynamic modeling in intracranial aneurysms: why computational fluid dynamics alone cannot solve the equation

Berg

Saalfeld²,

Voß

et al. 2019

Neurosurgical Focus

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Computational blood flow modeling in intracranial aneurysms (IAs) has enormous potential for the assessment of highly resolved hemodynamics and derived wall stresses. This results in an improved knowledge in important research fields, such as rupture risk assessment and treatment optimization. However, due to the requirement of assumptions and simplifications, its applicability in a clinical context remains limited.This review article focuses on the main aspects along the interdisciplinary modeling chain and highlights the circumstance that computational fluid dynamics (CFD) simulations are embedded in a multiprocess workflow. These aspects include imaging-related steps, the setup of realistic hemodynamic simulations, and the analysis of multidimensional computational results. To condense the broad knowledge, specific recommendations are provided at the end of each subsection.Overall, various individual substudies exist in the literature that have evaluated relevant technical aspects. In this regard, the importance of precise vessel segmentations for the simulation outcome is emphasized. Furthermore, the accuracy of the computational model strongly depends on the specific research question. Additionally, standardization in the context of flow analysis is required to enable an objective comparison of research findings and to avoid confusion within the medical community. Finally, uncertainty quantification and validation studies should always accompany numerical investigations.In conclusion, this review aims for an improved awareness among physicians regarding potential sources of error in hemodynamic modeling for IAs. Although CFD is a powerful methodology, it cannot provide reliable information, if pre- and postsimulation steps are inaccurately carried out. From this, future studies can be critically evaluated and real benefits can be differentiated from results that have been acquired based on technically inaccurate procedures.

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Section: Vessel Wall Conditionsmentioning

confidence: 99%

A review on the reliability of hemodynamic modeling in intracranial aneurysms: why computational fluid dynamics alone cannot solve the equation

Berg

Saalfeld²,

Voß

et al. 2019

Neurosurgical Focus

View full text Add to dashboard Cite

show abstract

“…The simulation of cerebral blood flow requires consideration of different aspects [10]. In the present study, the simulation is performed in a three-dimensional domain.…”

Section: Model Specificationsmentioning

confidence: 99%

Stresses Variation due to the Anomalies in Circle of Willis

Ghodsi¹,

Esfahanian²,

Dashtaki³

et al. 2015

TJSR

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The aneurysm is a complex phenomenon which is affected by different factors, such as the biological diseases and the blood flow parameters. The wall shear stress and pressure are the main factors in the establishment and growth of cerebral aneurysm. The circle of Willis is a prevalent location for aneurysm. On the other hand, the anomalies of circle of Willis cause variations in flow field pattern and also the wall shear stress and pressure. In the present study, the effects of some anomalies in the flow pattern are investigated using three dimensional simulation of the Circle of Willis. The simulations are conducted using commercial ANSYS FLUENT. The obtained results show the major anomalies cause increase wall shear stress and pressure on the wall of circle of Willis. This factor can lead to increase the risk of aneurysm.

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Numerical analysis of a brain artery in ANSYS

Carvalho

Bazani

2022

J Braz. Soc. Mech. Sci. Eng.

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Modeling Requirements for Computer Simulation of Cerebral Aneurysm

Cited by 5 publications

References 48 publications

A review on the reliability of hemodynamic modeling in intracranial aneurysms: why computational fluid dynamics alone cannot solve the equation

A review on the reliability of hemodynamic modeling in intracranial aneurysms: why computational fluid dynamics alone cannot solve the equation

Stresses Variation due to the Anomalies in Circle of Willis

Numerical analysis of a brain artery in ANSYS

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