“…The bioheat transmitting model was developed to measure the time-dependent temperature change as a heat reaction due to the usage of either heat source or thermal heating. The first model of biological tissues was found out by Pennes based on Fourier's law of heat conduction as follows 28 , 36 , 37 : where and are the density, specific heat, and thermal conductivity of the tissue, respectively. , and denote the specific heat of the blood, blood perfusion rate, blood density, and blood temperature, respectively.…”