Modeling magnetization transfer effects of Q2TIPS bolus saturation in multi-TI pulsed arterial spin labeling

Abstract

Magnetization transfer effects caused by bolus saturation pulses should not be ignored when performing quantification as they can cause appreciable underestimation of the CBF.

Fast imaging strategies for mouse kidney perfusion measurement with pseudocontinuous arterial spin labeling (pCASL) at ultra high magnetic field (11.75 tesla)

“…This might be explained by potential MT effects also reduced the relaxation time of both tissue and blood, and thus decreased the ASL signal, which may bias the BF quantification if not accounted for. 31 As an absolute quantitative technique, ASL could be a method of choice for perfusion measurements in the framework of longitudinal preclinical studies or for monitoring pharmacological manipulations in animal models. In this context, an important criterion is the reliability of the technique.…”

Multidelay ASL of the pediatric brain

“…[30][31][32] A number of protocol optimization techniques have been developed to reduce artefacts and improve contrast in MDASL. [33][34][35][36][37][38][39][40][41] CLINICAL APPLICATIONS Stroke Acute stroke can be arterial or venous in aetiology. Arterial infarcts are caused by stenosis or occlusion of arteries supplying brain tissue, reducing cerebral blood flow and leading to energy failure with cytotoxic parenchymal injury.…”