Modeling Blood Pulsatile Turbulent Flow in Stenotic Coronary Arteries

doi:10.46300/91011.2020.14.22

Cited by 7 publications

(15 citation statements)

References 36 publications

(73 reference statements)

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“…Moreover, in this location, the prevalence of recirculation zones is also verified [60,64,75,86,90,91]. Both high OSI, low WSS, and disturbed flows in the post stenotic section are important factors that can promote the formation of atherosclerotic plaques [59,68,92].…”

Section: Geometrical Parameters and Stenosis Severitysupporting

confidence: 56%

“…N.A-Not available. All images were adapted from [6,11,42,43,47,[57][58][59][60]64,[74][75][76][77][78][79][80][81][82][83][84][85][86][87][88]. N.A-Not available.…”

Section: Blood Flow Studies In Coronary Arteriesmentioning

confidence: 99%

“…Although various investigations consider the blood flow as laminar, due to the pulsatile nature of blood flow through arteries, and the presence of stenosis, the transition from laminar to turbulent flow condition can occur. For this reason, some authors have explored some turbulent models in computational simulations [42,59,64,77,78,86,96]. By observing Table 1 it can be seen that the majority uses or the standard k-ω or the k-ω SST turbulent model.…”

Section: Turbulence Modeling and Wall Assumptionsmentioning

confidence: 99%

“…Moreover, although considering the blood as a Newtonian fluid is generally accepted as a good approximation for large vessels, in the microcirculatory system, and also in the presence of stenosis, the assumption is not true. At these locations, the non-Newtonian behavior is more evident due to Over the years, researchers have modeled blood flow within arteries by using different geometries, diverging in two directions, using either stenotic geometries with idealized shapes (e.g., half-sphere [54], ellipsoid [55], gaussian equation [56], cosine function [57], among others proposed by the authors themselves [58,59]) or realistic coronary artery models extracted from patient's medical data [60][61][62][63][64][65].…”

Section: Introductionmentioning

confidence: 99%

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Blood Flow Modeling in Coronary Arteries: A Review

Carvalho

Pinho

Lima

et al. 2021

Fluids

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Atherosclerosis is one of the main causes of cardiovascular events, namely, myocardium infarction and cerebral stroke, responsible for a great number of deaths every year worldwide. This pathology is caused by the progressive accumulation of low-density lipoproteins, cholesterol, and other substances on the arterial wall, narrowing its lumen. To date, many hemodynamic studies have been conducted experimentally and/or numerically; however, this disease is not yet fully understood. For this reason, the research of this pathology is still ongoing, mainly, resorting to computational methods. These have been increasingly used in biomedical research of atherosclerosis because of their high-performance hardware and software. Taking into account the attempts that have been made in computational techniques to simulate realistic conditions of blood flow in both diseased and healthy arteries, the present review aims to give an overview of the most recent numerical studies focused on coronary arteries, by addressing the blood viscosity models, and applied physiological flow conditions. In general, regardless of the boundary conditions, numerical studies have been contributed to a better understanding of the development of this disease, its diagnosis, and its treatment.

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Section: Geometrical Parameters and Stenosis Severitysupporting

confidence: 56%

“…N.A-Not available. All images were adapted from [6,11,42,43,47,[57][58][59][60]64,[74][75][76][77][78][79][80][81][82][83][84][85][86][87][88]. N.A-Not available.…”

Section: Blood Flow Studies In Coronary Arteriesmentioning

confidence: 99%

Section: Turbulence Modeling and Wall Assumptionsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Blood Flow Modeling in Coronary Arteries: A Review

Carvalho

Pinho

Lima

et al. 2021

Fluids

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“…The first step necessary to study blood flow consisted in obtaining the threedimensional geometry of the lumen of an idealized coronary artery as depicted in Figure 1. This geometry was previously adopted in other works by these authors [27,28].…”

Section: Methodsmentioning

confidence: 99%

Comparison of CFD and FSI Simulations of Blood Flow in Stenotic Coronary Arteries

Carvalho¹,

Lopes²,

Silva³

et al. 2022

Applications of Computational Fluid Dynamics Simulation and Modeling

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Cardiovascular diseases are amongst the main causes of death worldwide, and the main underlying pathological process is atherosclerosis. Over the years, fatty materials are accumulated in the arterial which consequently hinders the blood flow. Due to the great mortality rate of this disease, hemodynamic studies within stenotic arteries have been of great clinical interest, and computational methods have played an important role. Commonly, computational fluid dynamics methods, where only the blood flow behavior is considered, however, the study of both blood and artery walls’ interaction is of foremost importance. In this regard, in the present study, both computational fluid dynamics and fluid-structure interaction modeling analysis were performed in order to evaluate if the arterial wall compliance affects considerably the hemodynamic results obtained in idealized stenotic coronary models. From the overall results, it was observed that the influence of wall compliance was noteworthy on wall shear stress distribution, but its effect on the time-averaged wall shear stress and on the oscillatory shear index was minor.

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