Model for end-stage liver disease (MELD) exception small-for-size syndrome

Model for end-stage liver disease (MELD) exception guidelines: Results and recommendations from the MELD exception study group and conference (MESSAGE) for the approval of patients who need liver transplantation with diseases not considered by the standard MELD formula

“…Small‐for‐size syndrome develops after primary living‐donor transplantation of a liver graft that either is of insufficient liver mass for the recipient or has a significant mismatch of vascular inflow to outflow. In both cases, severe synthetic dysfunction occurs, which has been associated with increased risk of death 25. There are no data available indicating whether these patients have different risks of dropout relative to other cases listed for retransplantation or whether the MELD/PELD score underestimates these patients' mortality risk relative to other waiting LT candidates.…”

Documento de consenso de la Sociedad Española de Trasplante Hepático. Lista de espera, trasplante pediátrico e indicadores de calidad

“…Small for size syndrome Este síndrome es el resultado de una insuficiente masa hepática; se manifiesta por coagulopatía, hiperbilirrubinemia y ascitis, y se asocia con una considerable mortalidad, por lo que debe priorizarse y recibir preferencia en los comités locorregionales de revisión 23 .…”