Model-based stimulation optimization for chronic pain suppression using percutaneous and surgical leads in spinal cord stimulation (SCS)

Computational Study of the Effect of Electrode Polarity on Neural Activation Related to Paresthesia Coverage in Spinal Cord Stimulation Therapy

“…The modeling study we present quantitatively compares the effect of electrode polarity (in single‐ and dual‐lead stimulation) on neural activation in SCS therapy and determines which one maximizes the activation area and depth in DC. To the best of our knowledge, there are some works that also studied the effect of polarity in SCS and even the effect of using a multiple current vs. single current source stimulation . However, this is the first study that considers and compares the effect of the most known and used electrode polarities in single‐ and dual‐lead stimulation (B1, B2, and GC) including, in addition, DGC polarity, which has never been compared to the previous polarities in SCS therapy.…”

“…We included a 3D representation of the DR, based on the DR model of Sankarasubramanian . To be more realistic, we included 80 DRs spaced 1 mm apart throughout the longitudinal axis of the volume conductor model (Fig.…”

Patient-specific computational modeling for spinal cord stimulation therapy optimization

“…The modeling study we present quantitatively compares the effect of electrode polarity in single-lead stimulation on neural activation in SCS therapy and determines which one maximizes the AA and AD in DC. To the best of our knowledge, there are some works that also studied the effect of polarity in SCS [60,92,93,125] and even the effect of using a multiple current versus single current source conductor model stimulation [78,104]. However, this is the first study that considers and compares the effect of the most known and used electrode polarities (B1, B2 and GC) including, in addition, DGC polarity.…”