Model-based estimation of optimal dissolved oxygen profile in Agrobacterium sp. fed-batch fermentation for improvement of curdlan production under nitrogen-limited condition

Zhang, Hongtao; Zhu, Li; Liu, Dengfeng; Zhan, Xi; Ding, Jian; Lin, Chi-Chung

doi:10.1016/j.bej.2015.06.012

Cited by 9 publications

(2 citation statements)

References 36 publications

(38 reference statements)

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“…PHAs can be synthesized by different living organisms, mainly bacteria and archaea, as a consequence of a survival mechanism to store energy during stressful and/or unfavorable growth conditions. , This implies, with the suitable selection of a microorganism, the synthesis of PHAs can be achieved from different substrates such as carbohydrates (e.g., glucose, fructose, sucrose), lipids (e.g., short fatty acids (or volatile fatty acids (VFAs), alcohols (e.g., glycerol, ethanol), and organic acids (e.g., butyric and propionic acids). ,− These substrates can, in turn, be found in or derived from a myriad of renewable feedstocks, including agro-industrial byproducts (such as bagasse, meals, peels, and leaves), food processing byproducts (such as waste oils, whey), or biorefining byproducts such as glycerol. All of these compounds have been tested as potential feedstocks for the industrial production of PHAs due to their high production volumes and low costs. − …”

Section: Challenges For the Commercialization Of Phasmentioning

confidence: 99%

Polyhydroxyalkanoates Production: A Challenge for the Plastic Industry

Guzmán-Lagunes,

Wongsirichot,

Winterburn

et al. 2023

Ind. Eng. Chem. Res.

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The accumulation of petroleum-based plastics in the environment has heightened the necessity of finding alternative materials with similar properties and lower environmental impact. Polyhydroxyalkanoates (PHAs) are a group of naturally occurring polyesters that have been investigated for several decades as potential substitutes for commonly used plastics. PHAs are biodegradable and biocompatible polymers derived from renewable resources. From this point of view, their industrial implementation represents an attractive strategy to reduce plastic pollution and petroleum dependency. Nevertheless, the high production costs related to these materials have considerably hindered their broader use and commercialization. In this regard, several approaches have been proposed to turn their production competitive from a commercial perspective. For instance, several studies have scrutinized the different production steps of PHAs in terms of economic viability. Reported strategies include optimization of fermentation processes; selection, isolation, and genetic modification of microbial strains; selection of low-cost renewable raw materials; and more efficient separation processes of the produced PHAs. This review summarizes the main advantages and disadvantages of different strategies proposed to improve the competitiveness of PHAs production; potential applications of PHAs manufactured by these different methods, as well as the main challenges to be overcome to develop economically viable industrial processes, are discussed in detail.

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Section: Challenges For the Commercialization Of Phasmentioning

confidence: 99%

Polyhydroxyalkanoates Production: A Challenge for the Plastic Industry

Guzmán-Lagunes,

Wongsirichot,

Winterburn

et al. 2023

Ind. Eng. Chem. Res.

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“…Curdlan is produced by Alcaligenes faecalis , Rhizobium radiobacter , and Agrobacterium species in a nitrogen-limiting environment with glucose or sucrose as the carbon source [ 172 , 173 , 174 , 175 ]. Factors known to affect curdlan biosynthesis include the nitrogen source, the carbon source, oxygen supply, and pH [ 176 , 177 , 178 , 179 ]. The carbon source also influences curdlan’s molecular weight and gel strength.…”

Section: Types and Properties Of Bacterial Exopolysaccharidesmentioning

confidence: 99%

Biomedical Applications of Bacterial Exopolysaccharides: A Review

et al. 2021

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Bacterial exopolysaccharides (EPSs) are an essential group of compounds secreted by bacteria. These versatile EPSs are utilized individually or in combination with different materials for a broad range of biomedical field functions. The various applications can be explained by the vast number of derivatives with useful properties that can be controlled. This review offers insight on the current research trend of nine commonly used EPSs, their biosynthesis pathways, their characteristics, and the biomedical applications of these relevant bioproducts.

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