Mode of Action of Selenium and Vitamin E in Prevention of Exudative Diathesis in Chicks

Noguchi, Tadashi; Cantor, A. H.; Scott, M. L.

doi:10.1093/jn/103.10.1502

Cited by 277 publications

(93 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The total antioxidative capability (TAOC) was measured by the FRAP assay (Benzie and Strain, 1996). The activity of glutathione peroxidase (GSH-Px), and the concentration of malondialdehyde (MDA) were measured according to the methods of Noguchi et al (1973) and Mak (1983), respectively. All data were analysed as a 2×2 factorial randomized block design using ANOVA procedure of SAS.…”

Section: Methodsmentioning

confidence: 99%

Effects of selenium on fatty acid concentration and antioxidant status of erythrocyte membrane in lambs fed linseed or sunflower oil diet

Yu¹,

Cao²,

Zhu³

et al. 2007

J. Anim. Feed Sci.

View full text Add to dashboard Cite

The effects of selenium and fatty acid supplementation on fatty acid composition and antioxidant status of erythrocyte membrane in lambs were investigated. Thirty two lambs with average body weight of 26±1 kg were divided into 4 groups and each was fed basal diet+5% linseed oil (LO), or LO+2 mg Se/ kg DM (as sodium selenite) (LOSe), or basal diet+5% sunflower oil (SO), or SO+2 mg Se/kg DM (SOSe). Selenium supplementation increased the concentration of C18:2t-10,c-12, and also the concentration of C20:5n-3 of erythrocyte membrane of the lambs fed the sunflower oil diet. Lambs fed the linseed oil diet had higher concentrations of C18:2t-10,c-12, C18:3n-3, and C20:5n-3 in erythrocyte membrane. Erythrocyte membrane of the lambs fed sunflower oil diet had higher concentrations of C18:1t-11, C18:2n-6, C18:2c-9,t-11 and C22:6n-3. Antioxidant status increased with selenium supplementation, and lambs fed sunflower oil diet had higher total antioxidative capability.

show abstract

Section: Methodsmentioning

confidence: 99%

Effects of selenium on fatty acid concentration and antioxidant status of erythrocyte membrane in lambs fed linseed or sunflower oil diet

Yu¹,

Cao²,

Zhu³

et al. 2007

J. Anim. Feed Sci.

View full text Add to dashboard Cite

show abstract

“…The definition of the activity unit takes account of the kinetic properties of the enzyme and allows an easy comparison of the results obtained with the coupled test system with those obtained with the different types of the fixed time assay. The proposed method requires only standard laboratory equipment and may be of great value in the investigation of genetic disorders (12,13,18,20) and selenium deficiency (5,8).…”

Section: Application Of the Test Proceduresmentioning

confidence: 99%

“…Glutathione peroxidase has been widely accepted as an integral part of the cellular antioxidative system (1)(2)(3)(4) and, recently, has turned out to be a selenoenzyme (5)(6)(7)(8)(9). Though determinations of glutathione peroxidase activity in human red blood cells have been carried out for several years (10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20), no assay for this enzyme activity has been developed, which can generally be accepted.…”

mentioning

confidence: 99%

An Improved Coupled Test Procedure for Glutathione Peroxidase (EC 1.11.1.9.) in Blood

Günzler¹,

Kremers²,

Flohé³

1974

Clinical Chemistry and Laboratory Medicine

237

159

View full text Add to dashboard Cite

An optimized coupled test system for glutathione peroxidase in red blood cells is presented. In the improved assay, tert. butyl hydroperoxide was employed as an acceptor substrate at twenty times K m ( app ) concentration. By aid of a batching procedure for instant separation of hemoglobin from glutathione peroxidase, it could be proved that cyanmethemoglobin in the modified procedure does not affect the spontaneous reaction rate. Further possible interference with the determination could be excluded. Glutathione peroxidase activities in red blood cells of normal adults were measured by the improved test method. A glutathione peroxidase activity in human plasma was observed.

show abstract

“…Entre os micronutrientes, a vitamina E é o mais importante antioxidante metabólico presente na membrana celular, e a protege da oxidação de ácidos graxos e do colesterol, além de diminuir ou inibir a produção e ação de radicais livres (Noguchi, 1973). De acordo com Tocher et al (2002) e Guerra et al (2004), menores quantidades de vitamina E nas dietas levam à diminuição de sua concentração nos músculos e ao aumento da atividade oxidante do organismo, o que resulta em altas concentrações de peróxidos lipídicos.…”

Section: Introductionunclassified

Desempenho produtivo de tambacus alimentados com dietas suplementadas com vitamina E

Gonçalves

Murgas

Rosa

et al. 2010

Pesq. agropec. bras.

View full text Add to dashboard Cite

Resumo -O objetivo deste trabalho foi avaliar os efeitos da suplementação da dieta de tambacus com concentrações de vitamina E sobre variáveis de desempenho e hematológicas, bem como determinar a relação da atividade da glutationa peroxidase com a inclusão de vitamina E e selênio na dieta. Foram utilizados 250 juvenis de tambacu, divididos em 25 aquários. A dieta basal constituiu-se de ração peletizada com 32% de proteína bruta e 3.300 kcal kg -1 de energia digestível, e inclusão de 0,40 mg kg -1 de Se. As dietas-teste − isoprotéicas e isoenergéticas − foram compostas da dieta basal com diferentes concentrações de vitamina E (0, 100, 200, 300, 400 mg kg -1 ), em delineamento inteiramente ao acaso, com cinco tratamentos e cinco repetições. Não foi observado efeito significativo da suplementação com vitamina E sobre o comprimento total, volume corpuscular médio, concentração de hemoglobina corpuscular média e número de eritrócitos, nem sobre a atividade da glutationa peroxidase. Peso final e conversão alimentar aparente, no entanto, sofreram efeito dos tratamentos suplementados. O teor de 400 mg kg -1 de vitamina E melhorou o comprimento padrão e ganho de peso. A suplementação da dieta com vitamina E resulta em melhor desempenho produtivo de tambacus.Termos para indexação: Colossoma macropomum, Piaractus mesopotamicus, enzimologia, hematologia, tocoferol. Productive performance of tambacus fed diets supplemented with vitamin EAbstract -The objective of this work was to evaluate the effects of tambacu vitamin E dietary supplementation on performance and hematological variables, and determine the relationship of glutathione peroxidase activity with vitamin E and selenium suplementation. Two hundred and fifty juvenile tambacus were used, divided into 25 aquaria. The basal diet was pelleted with 32% of crude protein and 3,300 kcal kg -1 of digestible energy, with 0.40 mg kg -1 Se. Test diets -isoproteic and isocaloric -were composed of the basal diet with increasing vitamin E concentrations (0, 100, 200, 300, 400 mg kg -1 ), in a completely randomized design, with five treatments and five replications. No significant effect of vitamin E supplementation was observed on total length, mean corpuscular volume, mean corpuscular hemoglobin concentration and total erythrocyte, and on the enzymatic activity of glutathione peroxidase. However, final weight and apparent feed conversion were significantly affected by supplemented treatments. Standard length and weight gain improved using diets supplemented with 400 mg kg -1 of vitamin E. Dietary vitamin E supplementation results in better tambacu performance.

show abstract

Mode of Action of Selenium and Vitamin E in Prevention of Exudative Diathesis in Chicks

Cited by 277 publications

References 19 publications

Effects of selenium on fatty acid concentration and antioxidant status of erythrocyte membrane in lambs fed linseed or sunflower oil diet

Effects of selenium on fatty acid concentration and antioxidant status of erythrocyte membrane in lambs fed linseed or sunflower oil diet

An Improved Coupled Test Procedure for Glutathione Peroxidase (EC 1.11.1.9.) in Blood

Desempenho produtivo de tambacus alimentados com dietas suplementadas com vitamina E

Contact Info

Product

Resources

About