Mobile Phone Text Messages and Effect on Treatment Adherence in Patients Taking Methotrexate for Rheumatoid Arthritis: A Randomized Pilot Study

Mary, Aurélien; Boursier, Amélie; Henry, I.; Grados, Franck; Séjourné, Alice; Salomon, Sarah; Fardellone, Patrice; Brazier, Michel; Goëb, Vincent

doi:10.1002/acr.23750

Cited by 31 publications

(40 citation statements)

References 36 publications

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“…A description of the quantitative evidence for the mHealth interventions reported in the included studies is presented in Table 1 . In the 10 intervention studies, four different types of interventions were used: SMS reminders (for adherence to medication and physical activity plans) [ 26 - 28 ], web apps (for information and disease monitoring) [ 13 , 29 - 32 ], smartphone apps (for disease monitoring) [ 8 ], and pedometers (for activity tracking) [ 33 ]. Measured outcomes and study methods varied among the trials, depending on the aim of the mHealth intervention.…”

Section: Resultsmentioning

confidence: 99%

“…Three RCTs investigated the use of SMS reminders. Mary et al [ 26 ] evaluated the impact of weekly text messages on medication adherence in patients taking methotrexate for RA. Study patients who received reminder text messages on the day they had to take their methotrexate had a greater increase in medication adherence, as assessed using the 9-item Compliance Questionnaire-Rheumatology (CQR-9), compared with a control group and a group receiving a 15-minute pharmacist counselling session [ 26 ].…”

Section: Resultsmentioning

confidence: 99%

“…With this review, we provide an overview of the effects of mHealth interventions tested in clinical trials in patients with RA. We identified 10 studies that examined 4 different types of mHealth tools [ 8 , 13 , 26 - 33 ]. Web apps were the most tested mHealth intervention [ 13 , 29 , 30 , 32 ].…”

Section: Discussionmentioning

confidence: 99%

“…The results of the studies in this review show that it is possible with mHealth interventions to effectively monitor patients to achieve remission sooner [ 31 ]. Also, by sending reminders, mHealth tools can motivate patients to improve medication compliance [ 26 ], as well as to be more physically active [ 13 , 28 , 33 ]. Furthermore, mHealth can improve the self-efficacy of patients with RA [ 8 , 30 , 32 ].…”

Section: Discussionmentioning

confidence: 99%

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Asynchronous mHealth Interventions in Rheumatoid Arthritis: Systematic Scoping Review

Seppen¹,

Boer²,

Wiegel³

et al. 2020

JMIR Mhealth Uhealth

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Background Mobile devices such as smartphones and tablets have surged in popularity in recent years, generating numerous possibilities for their use in health care as mobile health (mHealth) tools. One advantage of mHealth is that it can be provided asynchronously, signifying that health care providers and patients are not communicating in real time. The integration of asynchronous mHealth into daily clinical practice might therefore help to make health care more efficient for patients with rheumatoid arthritis (RA). The benefits have been reviewed in various medical conditions, such as diabetes and asthma, with promising results. However, to date, it is unclear what evidence exists for the use of asynchronous mHealth in the field of RA. Objective The objective of this study was to map the different asynchronous mHealth interventions tested in clinical trials in patients with RA and to summarize the effects of the interventions. Methods A systematic search of Pubmed, Scopus, Cochrane, and PsycINFO was performed following the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. Studies were initially screened and later assessed by two independent researchers. Disagreements on inclusion or exclusion of studies were resolved by discussion. Results The literature search yielded 1752 abstracts. After deduplication and screening, 10 controlled intervention studies were included. All studies were assessed to be at risk for bias in at least one domain of the Cochrane risk-of-bias tool. In the 10 selected studies, 4 different types of mHealth interventions were used: SMS reminders (to increase medication adherence or physical activity; n=3), web apps (for disease monitoring and/or to provide medical information; n=5), smartphone apps (for disease monitoring; n=1), and pedometers (to increase and track steps; n=1). Measured outcomes varied widely between studies; improvements were seen in terms of medication compliance (SMS reminders), reaching rapid remission (web app), various domains of physical activity (pedometer, SMS reminders, and web apps), patient-physician interaction (web apps), and self-efficacy (smartphone app). Conclusions SMS reminders, web apps, smartphone apps, and pedometers have been evaluated in intervention studies in patients with RA. These interventions have been used to monitor patients or to support them in their health behavior. The use of asynchronous mHealth led to desirable outcomes in nearly all studies. However, since all studies were at risk of bias and methods used were very heterogeneous, high-quality research is warranted to corroborate these promising results.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Asynchronous mHealth Interventions in Rheumatoid Arthritis: Systematic Scoping Review

Seppen¹,

Boer²,

Wiegel³

et al. 2020

JMIR Mhealth Uhealth

View full text Add to dashboard Cite

show abstract

“…Neben der reinen Datenerfassung kann über digitale Erinnerungsfunktionen oder Edukationsprogramme auch die Therapieadhärenz und das Krankheitsmanagement verbessert werden. So zeigte u. a. die Pilotstudie von Mary et al eine Verbesserung der Therapieadhärenz für die Einnahme von Methotrexat durch den Einsatz von SMS-Erinnerungen bei RA-Patienten [31].…”

Section: Apps Und Wearablesunclassified

Telemedizin in der Rheumatologie

Krusche

Muehlensiepen

Aries³

et al. 2020

Z Rheumatol

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Zusammenfassung Der Ausbruch der COVID-19-Pandemie geht mit tief greifenden Einschnitten im Alltag und im Berufsleben einher – sowohl gesamtgesellschaftlich als auch speziell im Gesundheitswesen. Im Fokus der Pandemieeindämmung haben sich vielerorts rheumatologische Routineabläufe verändert. Um den entsprechenden Infektionsschutz der Patienten und des medizinischen Personals gewährleisten zu können, wurde hier verstärkt Telemedizin (insbesondere Telefon- und Videosprechstunde) eingesetzt. Weiterhin stehen durch die Digitale-Gesundheitsanwendungen-Verordnung (DiGAV) voraussichtlich in den kommenden Monaten neue, abrechnungsfähige telemedizinische Anwendungsmöglichkeiten wie Apps und Wearables zur Verfügung. Der Artikel soll einen Überblick über telemedizinische Versorgungsmöglichkeiten in der Rheumatologie (mit besonderem Fokus auf die Videosprechstunde) geben. Weiterhin wird Bezug auf die vorhandene Evidenzlage sowie Chancen und Limitation der Telemedizin im Fachgebiet genommen.

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Outcomes and Quality of Care in Rheumatoid Arthritis With or Without Video Telemedicine Follow‐Up Visits

Ferucci

Day

Choromanski

et al. 2022

Arthritis Care & Research

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Telemedicine has been proposed to improve access to care in rheumatology, but few studies of telerheumatology have been published. The objective of this study was to evaluate outcomes and quality of care for rheumatoid arthritis (RA) in patients seen by video telemedicine follow-up compared to in-person only.Methods. Individuals in the Alaska Tribal Health System with a diagnosis of RA were recruited when seeing a rheumatologist either in-person or by video telemedicine, both of which were offered as part of usual followup care. At baseline, participants completed the Routine Assessment of Patient Index Data 3 (RAPID3) questionnaire and a telemedicine perception survey and agreed to medical record review. Participants repeated surveys by telephone at 6 and 12 months, and medical record abstraction was performed at 12 months for quality measures.Results. At the 12-month outcome assessment, 63 of 122 RA patients (52%) had ever used telemedicine for RA. In univariate analysis, functional status improved over 12 months in the telemedicine group. In multivariate analysis, RAPID3 score and functional status were associated with telemedicine group (higher), with no statistically significant change over the 12-month period. The only quality measure that differed between groups at 12 months in univariate analysis was the proportion of visits in which disease activity was documented (higher in the in-person group, 40% versus 25%; P = 0.02), but this was not significant after multivariate analysis.Conclusion. In short-term follow-up, there was no significant difference in most outcome and quality measures in patients with RA who incorporated telemedicine follow-up in their care compared to in-person only.The content herein is solely the responsibility of the authors and does not necessarily represent the official views of the Agency for Healthcare Research and Quality.

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Mobile Phone Text Messages and Effect on Treatment Adherence in Patients Taking Methotrexate for Rheumatoid Arthritis: A Randomized Pilot Study

Abstract: Our results evidenced a positive impact of text messages on adherence to MTX treatment for RA. The clinical benefit and the ideal target patient remain to be determined. This article is protected by copyright. All rights reserved.

Cited by 31 publications

References 36 publications

Asynchronous mHealth Interventions in Rheumatoid Arthritis: Systematic Scoping Review

Asynchronous mHealth Interventions in Rheumatoid Arthritis: Systematic Scoping Review

Telemedizin in der Rheumatologie

Outcomes and Quality of Care in Rheumatoid Arthritis With or Without Video Telemedicine Follow‐Up Visits

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