mNUTRIC tool is capable to predict nutritional needs and mortality early in patients suffering from severe pneumonia

Acehan, Selen; Gülen, Müge; Isıkber, Cem; Ünlü, Nurdan; Sümbül, Hilmi Erdem; Gulumsek, Erdinc; Satar, Salim

doi:10.1016/j.clnesp.2021.08.030

Cited by 6 publications

(6 citation statements)

References 31 publications

(38 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Early nutritional support in critically ill patients at high risk of malnutrition may improve patient outcomes [ 31 , 32 ]. Many studies have reported that the mNUTRIC score is a perfect tool for malnutrition status screening in critically ill patients, which may lead to undesirable outcomes [ 19 , 20 , 33 , 34 ] despite the mNUTRIC score does not include any nutrition-related factor. The mNUTRIC score is based on APACHE II, SOFA score, and comorbidities and serves as a more effective tool for predicting clinical outcomes.…”

Section: Discussionmentioning

confidence: 99%

“…In addition, the mNUTRIC score has been widely employed for screening clinical outcomes in critically ill patients, and its predictive accuracy for the 28-day mortality in septic patients is not inferior to the NUTRIC score [ 19 ]. The mNUTRIC score has also been proven as an effective tool for predicting ICU mortality in critically ill patients, including those with severe pneumonia [ 20 ] and sepsis [ 21 ]; however, studies have always declared small sample sizes and need further large sample size studies to elaborate the powerful evidence [ 19 , 22 , 23 , 24 ].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Significance of the Modified NUTRIC Score for Predicting Clinical Outcomes in Patients with Severe Community-Acquired Pneumonia

Tseng

Chen

et al. 2021

Nutrients

View full text Add to dashboard Cite

Nutritional status could affect clinical outcomes in critical patients. We aimed to determine the prognostic accuracy of the modified Nutrition Risk in Critically Ill (mNUTRIC) score for hospital mortality and treatment outcomes in patients with severe community-acquired pneumonia (SCAP) compared to other clinical prediction rules. We enrolled SCAP patients in a multi-center setting retrospectively. The mNUTRIC score and clinical prediction rules for pneumonia, as well as clinical factors, were calculated and recorded. Clinical outcomes, including mortality status and treatment outcome, were assessed after the patient was discharged. We used the receiver operating characteristic (ROC) curve method and multivariate logistic regression analysis to determine the prognostic accuracy of the mNUTRIC score for predicting clinical outcomes compared to clinical prediction rules, while 815 SCAP patients were enrolled. ROC curve analysis showed that the mNUTRIC score was the most effective at predicting each clinical outcome and had the highest area under the ROC curve value. The cut-off value for predicting clinical outcomes was 5.5. By multivariate logistic regression analysis, the mNUTRIC score was also an independent predictor of both clinical outcomes in SCAP patients. We concluded that the mNUTRIC score is a better prognostic factor for predicting clinical outcomes in SCAP patients compared to other clinical prediction rules.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Significance of the Modified NUTRIC Score for Predicting Clinical Outcomes in Patients with Severe Community-Acquired Pneumonia

Tseng

Chen

et al. 2021

Nutrients

View full text Add to dashboard Cite

show abstract

“…As a result, a modified NUTRIC (mNUTRIC) score was created, which incorporated all factors except the IL‐6 level 12 . Although the mNUTRIC score does not include any nutrition‐related factors, several studies have reported that the mNUTRIC score is an effective predictor of ICU mortality in critically ill patients 13–17 . The goal of the present study was to evaluate the association of mNUTRIC with mortality in critically ill patients with TBI.…”

Section: Introductionmentioning

confidence: 99%

Modified Nutrition Risk in the Critically ill score and mortality in critically ill patients with traumatic brain injury

Li,

Liu

et al. 2023

Nut in Clin Prac

View full text Add to dashboard Cite

BackgroundUnderstanding the relationship between nutrition risk at admission to the intensive care unit (ICU) and the prognosis of patients with traumatic brain injury (TBI) may aid early recognition of high‐risk patients.MethodsWe extracted data from the Medical Information Mart for Intensive Care III and the electronic ICU Collaborative Research Databases. Using modified Nutrition Risk in the Critically ill score (mNUTRIC) within the first 24 h of ICU admission, 5153 patients were divided into three groups: low (≤1, n = 1765), moderate (2–4, n = 2574), and high (≥5, n = 814). The primary outcome was 28‐day in‐hospital mortality, and the secondary outcomes were 7‐day in‐hospital mortality, length of ICU stay, and duration of mechanical ventilation.ResultsDuring the median follow‐up time of 6.69 days, 647 deaths occurred in total. After adjustment for potential confounding factors, setting the low mNUTRIC group as a reference, the risk of 28‐day mortality was increased in the high and moderate mNUTRIC groups (hazard ratio [HR]high vs low [95% CI]: 4.21 [2.70–6.58] and 2.84 [1.95–4.14], respectively). Similarly, high and moderate mNUTRIC scores are linked to a higher risk of 7‐day mortality (PTrend < 0.001) and a longer duration of mechanical ventilation (PTrend < 0.001). The effect of mNUTRIC on mortality varied by serum glucose level (PInteraction = 0.01). Lastly, those whose mNUTRIC scores deteriorated within the first 3 days have a 1.46 times greater risk of dying compared with patients with improved mNUTRIC scores.ConclusionsNutrition risk screening by mNUTRIC score at the time of admission to the ICU may improve mortality prediction.

show abstract

“…The AUC value of mNUTRIC (AUC: 0.681, 95% 0.582-0.780, p < 0.001) was higher than that of NRS-2002. While 64.8% (n = 81) of the patients were discharged, 35.2% (n = 44) died [7].…”

mentioning

confidence: 99%

“…It comprises age, number of comorbidities, days of hospitalization prior to being admitted to the critical care unit, the SOFA score (Sequential Organ Failure Assessment) and the APACHE II (Acute Physiology and Chronic Health Evaluation) score [6]. The prognostic power of the mNUTRIC Score has been previously analyzed with other indicators, as in the study by Acehan et al [7], in which the diagnostic precision of the mNUTRIC Score was compared with that of the NRS-2002 (Nutritional Risk Screening) to predict mortality in 125 patients with SARS-CoV-2 pneumonia during the COVID-19 pandemic. The AUC value of mNUTRIC (AUC: 0.681, 95% 0.582-0.780, p < 0.001) was higher than that of NRS-2002.…”

mentioning

confidence: 99%

Nutritional risk and lactate dehydrogenase: prognostic value for mortality and nosocomial infections in COVID-19 patients with respiratory distress syndrome.

Vinueza-Ortiz¹,

Gutiérrez-Salmeán

Hernández-Ortega

et al. 2023

Preprint

View full text Add to dashboard Cite

Background: In severe SARS-CoV-2 infection, lactate dehydrogenase (LDH) may be used to assess severity and mortality in patients with respiratory distress due to COVID-19. Thus a new nutritional screening index is proposed: the NUTRIC Score-LDH, which combines the prognostic value of the mNUTRIC Score and LDH to timely identify patients with a higher risk of malnutrition and contribute to the restoration of health through adequate nutrition support. Objective: The purpose of this study is to analyze the prognostic value of the combination of the mNUTRIC score with LDH to assess the risk of mortality and the development of infections in patients with COVID-19. Methodology: A prospective observational study was performed in patients infected with SARS-CoV-2 who presented respiratory distress syndrome. Chi-squared test (X2) was performed to identify the association among indicators of nutritional risk (mNUTRIC Score and the mNUTRIC Score-LDH), mortality and the presence of infections. Subsequently, prognostic values were determined and a Cox regression analysis was used to identify the risk of mortality adjusted for age, sex, body mass index, history of type II diabetes mellitus, arterial hypertension, and immunization for COVID-19. Results: A total of 257 patients participated, 63.8% were male. Mortality reached 38.1% (89). In terms of nutritional risk, 31.9% (82) had a high NUTRIC Score-LDH. The relative risk of a high mNUTRIC Score-LDH in terms of mortality was 4.578 p<0.0001 with a 95% confidence interval (3.226-6.496), while a high mNUTRIC Score had a risk of 3.86 p<0.0001 with a 95% confidence interval (2.92-5.03). mNUTRIC Score-LDH, has a sensibility of 0.80 and a specificity of 0.82 versus mNUTRIC Score with a sensibility of 0.56 and a specificity of 0.95. Conclusions: The NUTRIC Score-LDH is a valid indicator of the risk of mortality in patients with COVID-19 and respiratory distress syndrome who are at high risk of malnutrition.

show abstract

mNUTRIC tool is capable to predict nutritional needs and mortality early in patients suffering from severe pneumonia

Cited by 6 publications

References 31 publications

Significance of the Modified NUTRIC Score for Predicting Clinical Outcomes in Patients with Severe Community-Acquired Pneumonia

Significance of the Modified NUTRIC Score for Predicting Clinical Outcomes in Patients with Severe Community-Acquired Pneumonia

Modified Nutrition Risk in the Critically ill score and mortality in critically ill patients with traumatic brain injury

Nutritional risk and lactate dehydrogenase: prognostic value for mortality and nosocomial infections in COVID-19 patients with respiratory distress syndrome.

Contact Info

Product

Resources

About