1996
DOI: 10.1016/0009-2797(96)03702-7
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MNU affects mouse erythroleukemia cell differentiation at sub-cytotoxic doses

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Cited by 2 publications
(2 citation statements)
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“…Mice administered 75 mg/kg MNU exhibited significantly decreased body weights compared with those administered citrate buffer at 2-3 weeks after dosing. This body weight loss may be caused by the acute toxicity of this chemical [5]. Although the body weight of mice administered MNU gradually recovered, it remained lower than that of citrate buffer control animals at most time points.…”
Section: Body Weight and Haematological And Biochemistry Analysesmentioning
confidence: 93%
See 1 more Smart Citation
“…Mice administered 75 mg/kg MNU exhibited significantly decreased body weights compared with those administered citrate buffer at 2-3 weeks after dosing. This body weight loss may be caused by the acute toxicity of this chemical [5]. Although the body weight of mice administered MNU gradually recovered, it remained lower than that of citrate buffer control animals at most time points.…”
Section: Body Weight and Haematological And Biochemistry Analysesmentioning
confidence: 93%
“…The generation of adult T-cell leukaemia/lymphoma [3] and human acute B-lymphoblastic leukaemia [4] by xenotransplantation of primary peripheral blood mononuclear cells into combined immunodeficient mice were reported recently. In addition to the use of immunodeficient mice, irradiation or thymectomy have also been used to optimize models [5]. Genetically modified mice have also been studied intensively as potential lymphoma models [6][7][8][9][10] p53 is a well-known tumour suppressor gene, p53 knocked out mice appear spontaneous carcinogenesis [11].…”
Section: Introductionmentioning
confidence: 99%