Mixed Vesicle Formation on a Ternary Surfactant System:  Didodecyldimethylammonium Bromide/Dodecylethyldimethylammonium Bromide/Water

Abstract

The formation of mixed aggregates has been investigated on a ternary system consisting of two cationic surfactants with similar polar heads and two and/or one 12 carbon atom hydrophobic tail, respectively, didodecyldimethylammonium bromide and dodecylethyldimethylammonium bromide and water. The study has been carried out by means of conductivity, zeta potential, and cryogenic transmission electronic microscopy (cryo-TEM) experiments on the very diluted region. A variety of mixed aggregates, microaggregates, vesicles, and micelles has been found, depending on system composition and total surfactant concentration. Mixed critical microaggregate concentration and mixed critical vesicle concentration have been determined from conductivity data. Furthermore, zeta potential and cryo-TEM experiments allow for the characterization of the aggregates/solution interface and of the shape and size of the aggregates. This experimental evidence has also been analyzed in terms of the theoretical packing parameter, P.

Multicomponent folate-targeted magnetoliposomes: design, characterization, and cellular uptake

“…The major component, DOPC (47.5 mol%), had a PP = 1.08 and the cationic lipid, DPTAP (18.9 mol%), had a PP = 0.91 (average PP = 1.08). 32 Conical lipids (i.e. PP < 1) in heterogeneous liposomes can phase separate into regions that exhibit lower bending elasticity and, hence, adopt higher curvature.…”

Aggregation behavior in mixed system of double-chained anionic surfactant with single-chained nonionic surfactant in aqueous solution

“…In the past years, ionic/ionic, ionic/nonionic, nonionic/nonionic surfactant mixtures have been extensively investigated by different methods [1][2][3][4][5]. The mixed system almost invariably brings about enhanced interfacial properties compared to the single surfactant.…”

Modulation of Aggregation Behaviour of Amphiphlic Drug and Surfactant Mixture under the Influence of Neutral Polymer

“…The Γmax value is called the adsorption effectiveness and describes the adsorption tendency of surfactant molecules at the interface. The adsorption effectiveness is an important factor determining vital properties concerning foaming 26 , wetting emulsification 27 , solubilization 28 , drug delivery 29 and biological activities 30 . The higher the, steeper is the approach to cmc and higher is the surface activity values of surface excess.…”