Mixed anxiety–depression in a 1 year follow-up study: shift to other diagnoses or remission?

Barkow, Katrin; Heun, Reinhard; Wittchen, Hans‐Ulrich; Üstün, T. B.; Gänsicke, Michael; Maier, Wolfgang

doi:10.1016/s0165-0327(02)00343-9

Cited by 39 publications

(43 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Previous research has shown that in primary care, almost half of those with MAD at baseline had developed a threshold psychiatric disorder after a 1-year follow-up (Barkow et al, 2004). Thus, MAD was a prodromal stage in about half the cases.…”

Section: Limited Diagnostic Stability Over Timementioning

confidence: 96%

“…Thus, MAD was a prodromal stage in about half the cases. Of note, 27% had developed a depressive disorder, dysthymia, agoraphobia, panic disorder, or comorbid anxiety and depressive disorder, whereas another 22% fulfilled criteria of another ICD-10 disorder such as pain disorder, somatization disorder, hypochondriasis, neurasthenia, or alcohol disorders (Barkow et al, 2004). In addition, the results of a taxometric analysis reported the development of anxiety and depressive disorders over time (Schmidt et al, 2007).…”

Section: Limited Diagnostic Stability Over Timementioning

confidence: 99%

See 1 more Smart Citation

Mixed Anxiety Depression Should Not Be Included in DSM-5

Batelaan¹,

Spijker²,

Graaf³

et al. 2012

The Journal of Nervous and Mental Disease

View full text Add to dashboard Cite

Subthreshold anxiety and subthreshold depressive symptoms often co-occur in the general population and in primary care. Based on their associated significant distress and impairment, a psychiatric classification seems justified. To enable classification, mixed anxiety depression (MAD) has been proposed as a new diagnostic category in DSM-5. In this report, we discuss arguments against the classification of MAD. More research is needed before reifying a new category we know so little about. Moreover, we argue that in patients with MAD symptoms and a history of an anxiety or depressive disorder, symptoms should be labeled as part of the course trajectories of these disorders, rather than calling it a different diagnostic entity. In patients with incident co-occurring subthreshold anxiety and subthreshold depression, subthreshold categories of both anxiety and depression could be classified to maintain a consistent classification system at both threshold and subthreshold levels.

show abstract

Section: Limited Diagnostic Stability Over Timementioning

confidence: 96%

Section: Limited Diagnostic Stability Over Timementioning

confidence: 99%

Mixed Anxiety Depression Should Not Be Included in DSM-5

Batelaan¹,

Spijker²,

Graaf³

et al. 2012

The Journal of Nervous and Mental Disease

View full text Add to dashboard Cite

show abstract

“…Several studies have attempted to address the prevalence of anxiety disorders across separate older age groups. One study using a representative community sample, in Germany, found a 4.3% prevalence estimate for current anxiety disorders in those aged 70-84 years old compared to a 2.3% prevalence for current anxiety disorders in those aged [85][86][87][88][89][90][91][92][93][94][95][96][97][98][99][100][101][102][103]. [6] Similarly, Gum et al [5] used the NCS-R data to report that 8.0% of those 65-74 years old had an anxiety disorder in the past 12 months compared to 5.6% of those 75 years of age and older.…”

Section: Prevalence Of Anxiety Disorders Among Older Adultsmentioning

confidence: 99%

“…Furthermore, research has revealed a low prevalence for mixed anxiety-depression in the general adult population [98] as well as in primary care samples, [99] and demonstrated instability of the classification. [100] Thus, significantly more research is needed to develop and empirically test the construct of mixed anxietydepression in older adults before considering it as a diagnosis in its own right. Currently, these problems may be best described as NOS diagnoses.…”

Section: Comorbidity and Differential Diagnosismentioning

confidence: 99%

Anxiety disorders in older adults: a comprehensive review

Wolitzky-Taylor¹,

Castriotta²,

Lenze³

et al. 2010

Depress. Anxiety

533

398

View full text Add to dashboard Cite

This review aims to address issues unique to older adults with anxiety disorders in order to inform potential changes in the DSM-V. Prevalence and symptom expression of anxiety disorders in late life, as well as risk factors, comorbidity, cognitive decline, age of onset, and treatment efficacy for older adults are reviewed. Overall, the current literature suggests: (a) anxiety disorders are common among older age individuals, but less common than in younger adults; (b) overlap exists between anxiety symptoms of younger and older adults, although there are some differences as well as limitations to the assessment of symptoms among older adults; (c) anxiety disorders are highly comorbid with depression in older adults; (d) anxiety disorders are highly comorbid with a number of medical illnesses; (e) associations between cognitive decline and anxiety have been observed; (f) late age of onset is infrequent; and (g) both pharmacotherapy and CBT have demonstrated efficacy for older adults with anxiety. The implications of these findings are discussed and recommendations for the DSM-V are provided, including extending the text section on age-specific features of anxiety disorders in late life and providing information about the complexities of diagnosing anxiety disorders in older adults. Depression and Anxiety 27:190-211, 2010.

show abstract

“…In 1992, the International Classification of Diseases (ICD-10) introduced the concept of mixed anxiety and depressive disorder (MADD) (Barkow et al, 2004). Recent studies have reported that depression and anxiety may occur together with the association of subthreshold depressive symptoms and subthreshold depressive anxiety representing comorbid "pure" conditions.…”

Section: Introductionmentioning

confidence: 99%