Mitral valve lipomatous hamartoma: a rare entity

Francisco, Andreia; Gouveia, Rosa; Anjos, Rui

doi:10.1017/s1047951113001388

Cited by 4 publications

(1 citation statement)

References 9 publications

(25 reference statements)

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“…In the 21st century, Valvular Heart Disease may be isolated or affect multiple valves [5,6]; and its aetiology may include 10 nosologic groups: heritablecongenital, inflammatoryimmunologic, endocardial (infectious or not), myocardial or other organ diseases, neoplastic, degenerative, iatrogenic (even devices for valve repair or replacement), drugs and physical agents, infiltrative, and idiopathic [5,7,8]; all of which may underlie SCD, as showed by the cases reported.…”

Section: Discussionmentioning

confidence: 97%

Sudden cardiac death and valvular pathology

Gouveia¹,

Gonçalves²

2019

Forensic Sciences Research

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Sudden death due to valvular heart disease is reported to range from 1% to 5% in native valves and around 0.2%-0.9%/year in prosthesis. The nature of the diseases is varied, from heritable, congenital to acquired. It may affect both genders in multiple age groups. The authors show and comment examples of the major nosologic aetiologies underlying unexpected exitus letalis of valvular nature. ARTICLE HISTORY

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Section: Discussionmentioning

confidence: 97%

Sudden cardiac death and valvular pathology

Gouveia¹,

Gonçalves²

2019

Forensic Sciences Research

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Lipomatous hamartoma-like lesion of a bicuspid aortic valve: an incidental surgical finding

Martino¹,

Blasi²,

Lorenzini³

et al. 2016

Cardiovascular Pathology

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Pancreatic Lipomatous Hamartoma

Tanaka¹,

Ushiku²,

Ikemura³

et al. 2018

American Journal of Surgical Pathology

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Pancreatic masses consisting of lipomatous components clinically include lipoma, liposarcoma, lipomatous pseudohypertrophy of the pancreas, fat-containing neoplasms such as perivascular epithelioid cell tumor, and malignant neoplasm with lipoid degeneration. We present pancreatic lipomatous hamartoma, which has not been reported hitherto. A solid pancreatic mass was detected from a computed tomographic scan check-up in each of 3 cases of Japanese men. Macroscopically, well-demarcated solid lipomatous masses were detected at the uncus, body, and tail of the pancreas, respectively. Microscopically, the masses predominantly consisted of mature adipocytes with no atypia, but contained characteristics components of pancreatic hamartoma, such as small ducts, a well-preserved acinar structure, and/or fibrous stroma. On the basis of the unique features, lack of islets and absence of periductal elastic fibers, these tumors are a distinct variant of pancreatic hamartoma. Furthermore, high-mobility group AT-hook 2 expression in the fibro-adipocytes of this tumor indicated that these cells are an integral component of the pancreatic lipomatous hamartoma. Consequently, the unique tumors described herein are pancreatic lipomatous hamartoma, which must be discriminated from other lipomatous lesions of the pancreas.

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Mitral valve lipomatous hamartoma: a rare entity

Cited by 4 publications

References 9 publications

Sudden cardiac death and valvular pathology

Sudden cardiac death and valvular pathology

Lipomatous hamartoma-like lesion of a bicuspid aortic valve: an incidental surgical finding

Pancreatic Lipomatous Hamartoma

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