“…S3). [7][8][9][10][11][12][13][14][15][16][17][18] It is conceivable therefore that: (1) POA-containing species of PA, PS, PE, PC and PI could amass within the PM bilayer of yeast treated with POA; and (2) such buildup of POA-containing species of PL within the PM could alter the proper PL asymmetry in the PM bilayer and, thus, could induce the alkaline-pH-and lipid-asymmetryresponsive Rim101 signaling pathway.…”