Mitigation of antibiotic resistance in a pilot-scale system treating wastewater from high-speed railway trains

Wei, Ting; Yao, Hong; Sun, Peizhe; Cai, Weiwei; Li, Xinyang; Fan, Liru; Qing-chao, Wei; Lai, Cai; Guo, Jianhua

doi:10.1016/j.chemosphere.2019.125484

Cited by 15 publications

(5 citation statements)

References 69 publications

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“…As with aeroplane transport, wastewater produced in trains can contribute to the spreading of resistance genes. Wei and colleagues [40] investigated the efficiency of a pilot-scale system in removing ARGs and ARB in wastewater collected from multiple units of high-speed trains in Beijing (China). They showed that the abundance of ARGs and mobile genetic elements was similar to that of untreated hospital wastewater and higher than that of domestic wastewater.…”

Section: Resistomes In Trains and Metromentioning

confidence: 99%

The Bacterial Urban Resistome: Recent Advances

et al. 2022

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Cities that are densely populated are reservoirs of antibiotic resistant genes (ARGs). The overall presence of all resistance genes in a specific environment is defined as a resistome. Spatial proximity of surfaces and different hygienic conditions leads to the transfer of antibiotic resistant bacteria (ARB) within urban environments. Built environments, public transportation, green spaces, and citizens’ behaviors all support persistence and transfer of antimicrobial resistances (AMR). Various unique aspects of urban settings that promote spread and resilience of ARGs/ARB are discussed: (i) the role of hospitals and recreational parks as reservoirs; (ii) private and public transportation as carriers of ARGs/ARB; (iii) the role of built environments as a hub for horizontal gene transfer even though they support lower microbial biodiversity than outdoor environments; (iv) the need to employ ecological and evolutionary concepts, such as modeling the fate of a specific ARG/ARB, to gain enhanced health risk assessments. Our understanding and our ability to control the rise of AMR in an urban setting is linked to our knowledge of the network connecting urban reservoirs and the environment.

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Section: Resistomes In Trains and Metromentioning

confidence: 99%

The Bacterial Urban Resistome: Recent Advances

et al. 2022

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“…81 A more recent study used an O 3 concentration as high as 91 mg/L to disinfect wastewater from a high-speed railway train; five ARGs (tetA, tetG, qnrA, qnrS, bla NDM-1 ) were reduced by 1.67−2.49 log (an initial concentration of 4.35−7.78 log), and antibiotic-resistant enterococci was reduced by 3.16 log CFU/mL (an initial concentration of 6 log). 82 Another study summarized recent progresses on ozone application for enhanced wastewater treatment for chemical and biological contaminants, including DBP issues, elimination/disinfection efficiencies as a function of ozone doses or DOC normalized ozone dose. 83 The study found that disruption of iARGs was observed at specific ozone doses feasible for full-scale application, but may be interfered by flocs.…”

Section: Advances In Water Disinfection Technologies In Removing Arb ...mentioning

confidence: 99%

“…Xia et al used 25 mg/L O 3 to disinfect wastewater in a bioreactor and observed that the levels of multidrug, quinolone, mupirocin, polymyxin, aminoglycoside, glycopeptide, β-lactam, and trimethoprim resistance genes were reduced by more than 70% . A more recent study used an O 3 concentration as high as 91 mg/L to disinfect wastewater from a high-speed railway train; five ARGs ( tetA , tetG , qnrA , qnrS , bla NDM‑1 ) were reduced by 1.67–2.49 log (an initial concentration of 4.35–7.78 log), and antibiotic-resistant enterococci was reduced by 3.16 log CFU/mL (an initial concentration of 6 log) . Another study summarized recent progresses on ozone application for enhanced wastewater treatment for chemical and biological contaminants, including DBP issues, elimination/disinfection efficiencies as a function of ozone doses or DOC normalized ozone dose .…”

Section: Advances In Water Disinfection Technologies In Removing Arb ...mentioning

confidence: 99%

Traditional and Emerging Water Disinfection Technologies Challenging the Control of Antibiotic-Resistant Bacteria and Antibiotic Resistance Genes

Cai

Sun

et al. 2021

ACS EST Eng.

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The emergence of antibiotic-resistant bacteria (ARB) and antibiotic resistance genes (ARGs) in the environment has created obstacles when treating infectious diseases with antibiotics. Wastewater treatment plants (WWTPs) serve as reservoirs for ARB and ARGs and can disseminate them into the environment. It is important to understand and address these risks. Generally, professional disinfection processes have been used in WWTPs to disinfect the target water body, with the goal of eliminating pathogenic microorganisms in the water. However, ARGs are not generally considered, and antibiotic resistance has spread and developed through horizontal gene transfer (HGT). This Review provides a detailed overview of the application progress of different traditional and new disinfection technologies in removing ARB and ARGs, mainly focusing on the bacterial inactivation mechanisms of chlorination, ozonation, ultraviolet (UV) (including UVA, UVB, and UVC), sunlight, sunlight-dissolved organic matter (DOM), and photocatalysis (PC)/photoelectrocatalysis (PEC). In addition, this Review also focuses on the disinfection technology involved in the transfer of ARGs and clarifies the underlying transfer mechanisms in water environments. Furthermore, by linking the mechanisms of bacterial inactivation, the Review describes how SOS response and cell membrane permeability may be the key step in the conjugation, transformation, and transduction of ARGs. Finally, given the applications and current problems associated with traditional water disinfection technologies and light-based disinfection technologies in removing and controlling ARB and ARGs, this Review describes the current challenges and opportunities to facilitate the development of future disinfection technologies. The Review also highlights future research directions related to ARG transmission control.

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“…Diverse knowledge-based scape and research affirmed strategies have been reported by investigators and researchers with other strategies yet in the pipeline in the hope of giving a lasting solution to the problem of ARGs/MGEs in water bodies ( Kumar et al., 2020a , b ; Subirats et al., 2019; Jumat et al., 2018; Hu et al., 2018; Wen et al., 2018; Lu et al., 2018; Zhu et al., 2018; Kong et al., 2014). Some of those reported knowledge-scape were application of Ultraviolet (UV) and Ozone; application of aerated lagoon (AL) and biological nutrient removal (BNR) system; use of fabricated photo-catalytic reactive membrane (polyvinylidene fluoride ultrafiltration membrane) with titanium oxide nanoparticles; application of Galdieria sulphuraria which encourages the removal of ARG/MGE in algal-based wastewater treatment plant; use of powdered activated carbon; ultraviolet, chlorination, and ozone; granular activated carbon filtration (GACF); Fenton reaction in addition to UV irradiation; photocatalytic oxidation; Anaerobic membrane bioreactors (AnMBRs); Laboratory-scale electrochemical (EC); Ozonation, chlorination, chromatography-filtration with diethylaminoethyl-cellulose-monolithic column (C-FDECMC); Fe(II)-activated persulfate oxidation; modified HPC; combined coagulation-dissolved air flotation (DAF); Ultrasonic coupled bioleaching,UV-C/H 2 O 2 and Sunlight/H 2 O 2; Mobbing Bed Biofilm Reactor (MBBR); wastewater microbiomes fueling cells (WMFCs); newer innovative infrastructural systems (NIIS) etc, as all techniques revealed significant removal rate of ARGs/MGEs in wastewater treatment plants ( Ghernaout and Elboughdiri, 2020 ; Ghernaout and Ibn-Elkhattab, 2020 ; Krzeminski and Popowska, 2020 ; Lou et al., 2020 ; Li et al., 2020 ; Wei et al., 2020 ; Calderón-Franco et al., 2020 ; Qiu et al., 2020 ; Asadi-Ghalhari et al., 2020 ; Choi et al., 2020 ; Huang et al., 2020 ; Igere et al., 2020 ; Orimolade et al., 2020 ; Rizzo et al., 2019; Beheshti et al., 2019; Liu et al., 2019; Ravasi et al., 2019 ; Sun et al., 2019; Ren et al., 2018 ; Cheng et al., 2020 ; Ravasi et al., 2019 ; Jäger et al., 2018 ; Mane et al., 2018 ; McConnell et al., 2018 ; Zheng et al., 2017 ; van der Kooij et al., 2015 ; Chen and Zhang, 2013a , Chen and Zhang, 2013b Laht et al., 2014 Clauwaert et al., 2007 ).…”

Section: Introductionmentioning

confidence: 99%