Miscellaneous Skin Diseases

Scott, Danny W.

doi:10.1016/b0-72-162571-1/50016-7

Cited by 9 publications

(32 citation statements)

References 40 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Multiple factors have been implicated in the etiology of panniculitis in dogs, including bacterial and fungal infections, nutritional deficiency, vasculopathy, pancreatic disorders, and a variety of immunological (e.g., lupus erythematosus, drug eruption, etc.) and physicochemical (e.g., post-injection inflammation or trauma) factors [28]. In most cases, however, identifying the underlying causes of sterile panniculitis can be challenging, since it may be attributed to one of several causes, each of which may present with similar clinical and histopathological symptoms [34].…”

mentioning

confidence: 99%

“…The lesions may be localized to specific areas or generalized, and marked by deep cutaneous nodules that often ulcerate or fistulate, draining pustular, exudative, or oily substances. Systemic signs such as pyrexia, anorexia, lethargy, and depression are often associated with generalized panniculitis and commonly manifest in waves, heralding the eruption of new lesions [11,28]. Multiple factors have been implicated in the etiology of panniculitis in dogs, including bacterial and fungal infections, nutritional deficiency, vasculopathy, pancreatic disorders, and a variety of immunological (e.g., lupus erythematosus, drug eruption, etc.)…”

mentioning

confidence: 99%

See 1 more Smart Citation

A Retrospective Study and Gene Analysis of Canine Sterile Panniculitis

Yamagishi

Momoi

Kobayashi

et al. 2007

The Journal of Veterinary Medical Science

View full text Add to dashboard Cite

ABSTRACT. In this study, a retrospective analysis was conducted to assess the current aspects and predisposing factors of canine sterile panniculitis. Miniature dachshund, neutered, and younger dogs appeared to be predisposed. In addition, histories of previous surgery and injection were associated in 46.5% of the cases, with several types of surgical suture materials used. About 88% of the dogs had multifocal lesions, frequently with signs of systemic illnesses. Whereas systemic immunosuppressive therapy was effective in most dogs, surgical excision of lesions was rarely curative. In order to prevent recurrences, over 65% of the cases required prolonged immunosuppressive therapy. Polymorphism of canine α 1 AT gene was investigated as a candidate gene for sterile panniculitis. Eight polymorphisms were discovered in seven Miniature dachshunds by direct nucleotide sequencing, which included a 12-bp deletion, three non-synonymous single nucleotide polymorphisms, and four silent substitutions. Genotyping of the two polymorphisms, c.109_120del12 and c.483A>C, which identified at high incidence in the dachshunds, was conducted in 83 dogs of 6 popular breeds. The frequencies of neither polymorphism differed between Miniature dachshunds and other breeds, suggesting that neither is responsible for developing panniculitis. KEY WORDS: miniature dachshund, panniculitis, polymorphism, surgery.J. Vet. Med. Sci. 69(9): 915-924, 2007

show abstract

mentioning

confidence: 99%

mentioning

confidence: 99%

A Retrospective Study and Gene Analysis of Canine Sterile Panniculitis

Yamagishi

Momoi

Kobayashi

et al. 2007

The Journal of Veterinary Medical Science

View full text Add to dashboard Cite

show abstract

“…Although the appearance of the cutaneous lesions of this dog were, also, reminiscent of erythema multi forme, cutaneous vasculitis and perhaps of urticaria, their histopathologic picture is different than that of EDE (Scott et al 2001, Gross 2005. Multiple ery thema (lymphocytic interface dermatitis with keratinocyte apoptosis occurring in all epidermal layers plus lymphocytic satellitosis) and cutaneous vasculitis (vascular thrombosis, perivascular hemorrhage, intramular changes) were ruled out with the aid of histo pathology (Gross 2005).…”

Section: Discussionmentioning

confidence: 99%

“…Surprisingly, dermal hemorrhage, as suggested by the clinical findings, was not present in this dog, as it has, also, been reported before (Holm et al 1999). On the other hand, the absence of lesions' blanching on diascopy ruled out beforehand urticaria as a diagnostic option, apart from the fact of their persistence, morphology and variation (Scott et al 2001, Gross 2005. Consequently, the cutaneous reaction presented by this dog did not fit either the clinical criteria of Wells' syndrome in humans or the typical type 1 hypersensitivity-urticarial reaction (Mauldin et al 2006) and it seems to be unique to the canine species.…”

Section: Discussionmentioning

confidence: 99%

“…In this type of dermatitis, eosinophils predominate in the inflammatory infiltrate which is localized in the dermis and/or subcutis (Scott et al 2001, Leiferman andPeters 2007). Eosinophils, named after the affinity of their granules for eosin (Harvey 2001, Bloom 2006, have phagocytic properties, engulfing immune complexes, mast cell granules, aggregated immunoglobulins and certain bacteria and fungi (Grodecki 2000, Scott et al 2001. In order to fulfill their function, eosinophils degranulate potent molecules, such as major basic protein, eosinophil per oxidase and eosinophilic-derived neurotoxin (Monello 2003, Raskin et al 2004, Bloom 2006, Leiferman and Peters 2007).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Eosinophilic dermatitis with edema (WellsMike syndrome) possibly triggered by cooked fish in a dog

Giannoulopoulos

Farmaki

Koutinas

et al. 2017

J Hellenic Vet Med Soc

View full text Add to dashboard Cite

A 2-year old intact female mongrel dog was admitted with multifocal skin lesions appearing suddenly and extending symmetrically over most of the body. The dog was living indoors and one day before the admission it had consumed cooked fish. Neither medication, nor vaccination had been given to the dog, at least during the last 3 months. Physical examination revealed only non-pruritic and non-painful macules, papules and plaques that were distributed mainly over the head, pinnae, neck and thorax. The lesions were annular, aeriform or serpiginous with a tendency to coalesce. Skin histopathology (H-E) revealed a superficial dermal edema, post-capillary venule congestion and perivascular to interstitial eosinophilic dermatitis as the main pattern. The dog was initially placed on oral vitamin E, sulphasalazine and doxycycline, but to no avail. As soon as the diagnosis of eosinophilic dermatitis with edema was confirmed by histopathology, the former treatment stopped and oral prednisolone was given for two months during which there was a remarkable improvement of skin lesions and complete disappearance with no relapse. The cooked fish, consumed by the dog the night before the incident, was assumed to be the cause of the acute eosinophilic hypersensitivity reaction.

show abstract

Randomised controlled trial of the treatment of pastern dermatitis with a formulation containing kunzea oil

et al. 2009

View full text Add to dashboard Cite

The efficacy of an ointment containing kunzea oil for the treatment of horses with localised acute or chronic pastern dermatitis was assessed. Thirty-seven horses were randomly allocated to treatment with an ointment containing either 20 per cent kunzea oil (test) or 2 per cent ketoconazole (control). Only 21 of the horses completed the study. The severity of the lesions was assessed before and after seven days of treatment. The kunzea oil formulation resulted in a significant decrease in the median total area of the lesions from 40 cm(2) (range 3 to 252 cm(2)) to 0 cm(2) (range 0 to 34 cm(2)), with complete resolution of the signs of pastern dermatitis in seven of 11 cases. The control formulation resulted in no significant change in the total area of the lesions, and the signs of pastern dermatitis resolved completely in only two of the 10 cases.

show abstract

Miscellaneous Skin Diseases

Cited by 9 publications

References 40 publications

A Retrospective Study and Gene Analysis of Canine Sterile Panniculitis

A Retrospective Study and Gene Analysis of Canine Sterile Panniculitis

Eosinophilic dermatitis with edema (WellsMike syndrome) possibly triggered by cooked fish in a dog

Randomised controlled trial of the treatment of pastern dermatitis with a formulation containing kunzea oil

Contact Info

Product

Resources

About