Minor eudesmanolides from Artemisia canariensis

Three New Sesquiterpenoids from Echinops ritro L.

“…1, b). These findings showed that the relative configuration of HÀC(1), HÀC(3), HÀC(4), HÀC(5), and HÀC (6) in 1 was a, b, b, a, and C-NMR (Table 1) disclosed a guaianetype skeleton [13]. The structure of 2 was established from the 1 H-and (9) (Fig.…”

“…HÀC (1) eno-12,6-lactone [13], except for C(7), C(11), C(13), and C(3), which suggested they have similar structures. In the 13 C-NMR spectrum, the signals of C(7) and C(11) were shifted downfield from d(C) 55.7 and 74.5 in [13] to d(C) 170.4 and 126.1 in 1, which suggested that there is a C¼C bond in 1 instead of single bond.…”

“…In the 13 C-NMR spectrum, the signals of C(7) and C(11) were shifted downfield from d(C) 55.7 and 74.5 in [13] to d(C) 170.4 and 126.1 in 1, which suggested that there is a C¼C bond in 1 instead of single bond. The signal of C(13) was shifted downfield from d(C) 21.6 in [13] to d(C) 53.7 in 1, meanwhile it was transformed into a CH 2 group from a Me group, which suggested that there is a CH 2 OH group in 1 instead of a Me group.…”

“…In the 13 C-NMR spectrum, the signals of C(7) and C(11) were shifted downfield from d(C) 55.7 and 74.5 in [13] to d(C) 170.4 and 126.1 in 1, which suggested that there is a C¼C bond in 1 instead of single bond. The signal of C(13) was shifted downfield from d(C) 21.6 in [13] to d(C) 53.7 in 1, meanwhile it was transformed into a CH 2 group from a Me group, which suggested that there is a CH 2 OH group in 1 instead of a Me group. This was further confirmed by the HMBCs CH 2 (2)/C(1), C(3), C(4), and C(5), HÀC(4)/C(1), C(2), C(5), C(6), and C(15), HÀC(5)/C(1), C(4), C(6), C(7), and C(15), CH 2 (14)/C(1) and C(9), CH 3 (15)/C(3), C(4) and C(5), and CH 2 (13)/C(7), C(1l), and C(12), and the 1 H, 1 H-COSY data confirmed the connectivity of C(1) to C(2) and C(5), of C(3) to C(2) and C(4), of C(5) to C(4) and C(6), and of C(8) to C(7) and C(9) (Fig.…”

Diuretic activity of Artemisia thuscula, an endemic canary species

“…Partial studies have been carried out on the chemical composition of Artemisia thuscula, having isolated eudesmanolides, a type of sesquiterpene lactone (González et al, 1983;Breton et al, 1985;Mansilla and Palenzuela, 1999), and essential oil (Bellomaria et al, 1993).…”