Minireview: Therapeutic potential of myricetin in diabetes mellitus

Li, Yong; Ding, Ye

doi:10.1016/j.fshw.2012.08.002

Cited by 121 publications

(76 citation statements)

References 61 publications

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“…Myricetrin has been shown to regulate intestinal glucose uptake (Postal et al 2014) and weight gain (Maronpot et al 2015), while its metabolite (myricetin) is widely acknowledged to have antidiabetic properties mediated via improvements in glycemia, weight and lipid profiles, antioxidation and aldose reductase inhibition (Li & Ding 2012;Ong & Khoo 1997), similar to the effects observed in this study. In aggregate, our data showed that R. Cinerea could improve metabolic perturbations in Type 2 diabetic rats.…”

Section: Hplc Bioactive Identificationsupporting

confidence: 71%

Effects of the Aqueous Extracts of Rhodamnia cinerea on Metabolic indices and Sorbitol-Related Complications in Type 2 Diabetic Rats

Imam¹,

Ismail²,

Chinnappan³

2017

JSM

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Section: Hplc Bioactive Identificationsupporting

confidence: 71%

Effects of the Aqueous Extracts of Rhodamnia cinerea on Metabolic indices and Sorbitol-Related Complications in Type 2 Diabetic Rats

Imam¹,

Ismail²,

Chinnappan³

2017

JSM

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“…Myricetin exhibits antibacterial, anti-gonadotropic, antioxidant [34], anti-carcinogenic, anti-diabetic, antihyperlipidemic, anti-inflammatory, antimicrobial, antioxidant, anti-platelet, antiviral and cytoprotective [53] activities. Biochanin A has been reported to have anticancer, anti-inflammatory, antimicrobial, antioxidant, immunomodulatory and hepatoprotective [54] activities.…”

Section: Discussionmentioning

confidence: 99%

Phytochemical Composition of <i>Tridax procumbens</i> Linn Leaves: Potential as a Functional Food

Ikewuchi¹,

Ikewuchi²,

Ifeanacho³

2015

FNS

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The leaves of Tridax procumbens were screened for the presence of bioactive molecules. They had high flavonoids, alkaloids, hydroxycinnamates, tannins and phytosterols, moderate benzoic acid derivatives and lignans, and low carotenoids contents. Thirty nine known alkaloids (mainly akuammidine, 68.756%), twenty three known flavonoids (mainly 17.593% kaempferol and 12.538% (−)-epicatechin), five known carotenoids (mainly lutein, 62.608%), four known benzoic acid derivatives (mainly ferulic acid, 46.091%), two phytosterols (mainly stigmasterol, 80.853%) and six known lignans (mainly galgravin, 77.326%) were detected. Also detected were caffeic acid and tannic acid. The medicinal properties of the flavonoids, phytosterols, alkaloids, tannins, hydroxicinnamates, carotenoids, benzoic acid derivatives and lignans that were present in the leaves were discussed herein and proposed to be explored for their potential medicinal values. The great number of potentially active nutrients and their multifunctional properties make Tridax procumbens a perfect candidate for the production of health-promoting food and food supplements.

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“…Myricetin is a naturally occurring flavonol, a flavonoid found in many grapes, berries, fruits, vegetables, herbs, as well as other plants, which possesses antioxidant, antifungal, antiviral, anticancer activities [1][2][3]. But the poor solubility and stability of myricetin in water restricted its application as an antioxidant and functional supplement in hydrophilic food.…”

Section: Introductionmentioning

confidence: 99%

Physiochemical properties of the complex of myricetin and hydroxypropyl-β-cyclodextrin

Nan¹,

Ma²,

Zhang³

et al. 2014

Trop. J. Pharm Res

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Purpose: To improve the hydrophilic property of myricetin by complexing it with hydroxypropyl-β-cyclodextrin (HP-β-CD) Methods: The complexes of myricetin and HP-β-CD were prepared in both water and ethanol. The physicochemical properties of the complex were investigated by ultraviolet-visible spectrometry (UV), Fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), differential scanning calorimetry (DSC) and x-ray diffractometry (XRD). Results: The content of myricetin in the complex prepared in ethanol (3.71 %) was higher than that prepared in water (1.43 %). Characterization studies indicate that myricetin in the complex was molecularly dispersed in HP-β-CD matrix. Conclusion:Ethanol is the better solvent to prepare the complex of myricetin and hydroxypropyl-β-cyclodextrin. Myricetin and HP-β-CD in the complex are combined by non-covalent bond, and thus did not form a new compound.

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Minireview: Therapeutic potential of myricetin in diabetes mellitus

Cited by 121 publications

References 61 publications

Effects of the Aqueous Extracts of Rhodamnia cinerea on Metabolic indices and Sorbitol-Related Complications in Type 2 Diabetic Rats

Effects of the Aqueous Extracts of Rhodamnia cinerea on Metabolic indices and Sorbitol-Related Complications in Type 2 Diabetic Rats

Phytochemical Composition of <i>Tridax procumbens</i> Linn Leaves: Potential as a Functional Food

Physiochemical properties of the complex of myricetin and hydroxypropyl-β-cyclodextrin

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Minireview: Therapeutic potential of myricetin in diabetes mellitus

Cited by 121 publications

References 61 publications

Effects of the Aqueous Extracts of Rhodamnia cinerea on Metabolic indices and Sorbitol-Related Complications in Type 2 Diabetic Rats

Effects of the Aqueous Extracts of Rhodamnia cinerea on Metabolic indices and Sorbitol-Related Complications in Type 2 Diabetic Rats

Phytochemical Composition of &lt;i&gt;Tridax procumbens&lt;/i&gt; Linn Leaves: Potential as a Functional Food

Physiochemical properties of the complex of myricetin and hydroxypropyl-β-cyclodextrin

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Phytochemical Composition of <i>Tridax procumbens</i> Linn Leaves: Potential as a Functional Food