Minireview Magnetically controlled targeted micro-carrier systems

A new procedure for preparation of polyethylene glycol-grafted magnetic iron oxide nanoparticles

“…The magnetite nanoparticles were synthesized through the co-precipitation of ferrous and ferric hydroxides by addition of NH 4 OH to a solution of Fe(II) and Fe(III) salts at a 1:2 molar ratio under nitrogen atmosphere to prevent oxidation. Scanning electron microscopy was used to illustrate the morphology of magnetite nanoparticles.…”

“…Magnetic iron oxide nanoparticles with tailored surface chemistry have been widely used experimentally for numerous in vivo applications such as magnetic resonance imaging, contrast enhancement, tissue repair, immunoassay, detoxification of biological fluids, hyperthermia, drug delivery and in cell separation [1][2][3][4][5]. Coating or modifying these nanoparticles with hydrophilic molecules, especially biomolecules, is a crucial step for the preparation of waterdispersible magnetite nanoparticles (MNPs) for use in biological applications [6].…”

Brain Drug Delivery Systems for Neurodegenerative Disorders

“…In order to produce a depot in the target organ, a suitable magnet was kept (8000 Gaussauss/cm strength) on the head. It has been suggested that at the arterio-capillary blood flow rate of 0.005-0.1 cm/s, 20% (w/w) magnetite is sufficient to achieve 100% retention of the magnetic carrier using 8000 Gauss magnet [95], and these microparticles presented a magnetite content of 30% (w/w). There was a reduction in the accumulation of tacrine in the non-targeted organs liver, spleen and kidneys, when it was administered in the form of magnetic chitosan microparticles, compared to the free drug tacrine.…”

Synthesis of Magnetic Polystyrene-Polyimide Core-Shell Microsphere

“…초상 자성 재료는 강자성 재료에 비해 낮은 잔류자화와 보자력 값 을 갖기 때문에 인가된 자장에 민감하게 반응하여 cell separation, 1,2 cell labeling, [3][4][5] enzyme immunoassays, 6 nucleic acids concentration, 7 drug delivery processes, 8 …”