Miniopen Repair of Ruptured Achilles Tendon in Diabetic Patients

Eid, Abdelsalam

doi:10.1155/2014/840369

Cited by 3 publications

(3 citation statements)

References 12 publications

(26 reference statements)

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“…Indeed, patients with Achilles tendon rupture have higher concentrations of cholesterol ( 56 ), and biopsies from patients with AT exhibit increased levels of the esterified fraction of cholesterol ( 57 ). In addition, a higher incidence of diabetes has been reported in individuals with Achilles tendon ruptures, suggesting its involvement in the pathogenesis of AT ( 58 ). Renal dysfunction has also been proposed as an independent risk factor for AT in patients who have received a heart transplant ( 59 ).…”

Section: Discussionmentioning

confidence: 99%

Causal Associations of Obesity With Achilles Tendinopathy: A Two-Sample Mendelian Randomization Study

Zhang

et al. 2022

Front. Endocrinol.

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BackgroundAchilles tendinopathy (AT) is associated with severe pain and is the cause of dysfunction and disability that are associated with significant reduction in social and economic benefits. Several potential risk factors have been proposed to be responsible for AT development; however, the results of observational epidemiological studies remain controversial, presumably because the designs of these studies are subject to residual confounding and reverse causality. Mendelian randomization (MR) can infer the causality between exposure and disease outcomes using genetic variants as instrumental variables, and identification of the causal risk factors for AT is beneficial for early intervention. Thus, we employed the MR strategy to evaluate the causal associations between previously reported risk factors (anthropometric parameters, lifestyle factors, blood biomarkers, and systemic diseases) and the risk of AT.MethodsUnivariable MR was performed to screen for potential causal associations between the putative risk factors and AT. Bidirectional MR was used to infer reverse causality. Multivariable MR was conducted to investigate the body mass index (BMI)-independent causal effect of other obesity-related traits, such as the waist-hip ratio, on AT.ResultsUnivariable MR analyses with the inverse-variance weighted method indicated that the genetically predicted BMI was significantly associated with the risk of AT (P=2.0×10-3), and the odds ratios (95% confidence intervals) is 1.44 (1.14−1.81) per 1-SD increase in BMI. For the other tested risk factors, no causality with AT was identified using any of the MR methods. Bidirectional MR suggested that AT was not causally associated with BMI, and multivariable MR indicated that other anthropometric parameters included in this study were not likely to causally associate with the risk of AT after adjusting for BMI.ConclusionsThe causal association between BMI and AT risk suggests that weight control is a promising strategy for preventing AT and alleviating the corresponding disease burden.

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Section: Discussionmentioning

confidence: 99%

Causal Associations of Obesity With Achilles Tendinopathy: A Two-Sample Mendelian Randomization Study

Zhang

et al. 2022

Front. Endocrinol.

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“…Com relação ao ATRS-BR foi observada uma média de escore de 54,6 pontos. Segundo o trabalho de Eid (13) , pacientes com diabetes tipo 2, com idade média de 54,8 anos (variando de 47 a 65 anos), com diagnóstico de ruptura degenerativa do Aquiles, foram avaliados e apresentaram escore ATRS de 15,1 (intervalo: 11 a 22). Nos pacientes do presente estudo, pertencentes a uma população semelhante em relação a comorbidades e idade, nota-se um ATRS médio de 54,6 pontos, maior que no trabalho citado anteriormente (13) .…”

Section: Discussionunclassified

Functional and quality of life assessment of patients with ankle ulcers subjected to complete Achilles tendon resection

et al. 2019

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Objective: To assess the quality of life and functional status of patients subjected to debridement of ulcers in the posterior ankle who required complete Achilles tendon resection without any type of reconstruction or tendon transfer. Method: This is a case series of 5 (mostly diabetic) patients who underwent complete Achilles tendon resection due to an ulcer in the posterior ankle region. Preservation of the Achilles tendon was prevented due to tendon exposure, extensive degeneration and the need for infection control. Patients answered the Brazilian Portuguese version of the Achilles Tendon Total Rupture Score (ATRS-BR) questionnaire and the 36-item Short-Form Health Survey (SF-36) during the postoperative period, and follow-up varied between 6 and 24 months. The ATRS-BR ranges from 0 to 100, and higher scores indicate fewer symptoms and limitations. The SF-36 consists of 36 questions comprising 8 domains, which are independently assessed and given a score of up to 100 points, with higher scores indicating better health status. Results: The mean age of patients was 70 years. The mean score on the SF-36 physical functioning domain was 70 (50-95) points. The mean value of the ATRS-BR was 54.6 (31-88) points; however, the patients had few complaints about their functional status. Conclusion: Non-reconstruction of the Achilles tendon in predominantly diabetic elderly patients with posterior ankle ulcers presents encouraging functional outcomes. This study suggests that complete Achilles tendon resection is a viable option for ulcer treatment in this population. Level of Evidence IV; Therapeutic Studies; Cases Series.

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“…Several other studies involving patients diagnosed with diabetes found that patients developed superficial wound infections after percutaneous repair as well as a mini-open repair. (19,20).…”

Section: Diabetesmentioning

confidence: 99%

ACFAS Clinical Consensus Statement: Acute Achilles Tendon Pathology

Naldo

Agnew

Brucato³

et al. 2021

The Journal of Foot and Ankle Surgery

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Injuries to the Achilles tendon are a challenge to the foot and ankle surgeon. In recent years, research has led to a relative change in the way that many surgeons view acute Achilles tendon rupture. In an effort to fully evaluate these trends, as well as to evaluate all aspects of care for acute Achilles tendon rupture, the American College of Foot and Ankle Surgeons convened a panel of experts to create a clinical consensus statement to address selected aspects of care of the acute Achilles tendon injury.

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Miniopen Repair of Ruptured Achilles Tendon in Diabetic Patients

Cited by 3 publications

References 12 publications

Causal Associations of Obesity With Achilles Tendinopathy: A Two-Sample Mendelian Randomization Study

Causal Associations of Obesity With Achilles Tendinopathy: A Two-Sample Mendelian Randomization Study

Functional and quality of life assessment of patients with ankle ulcers subjected to complete Achilles tendon resection

ACFAS Clinical Consensus Statement: Acute Achilles Tendon Pathology

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