Minimally Invasive Treatment of Gastric Gastrointestinal Stromal Tumors

Jeong, In Ho; Kim, Ji Hun; Lee, Sang-Rim; Kim, Jin Hong; Hwang, Jae Chul; Shin, Sung Jae; Lee, Kee Myung; Hur, Hoon; Han, Sang Uk

doi:10.1097/sle.0b013e31825078f2

Cited by 56 publications

(46 citation statements)

References 25 publications

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“…11 If GISTs are located in duodenum, more extensive resection, such as pyloruspreserving pancreaticoduodenectomy (PPPD), might be necessary due to anatomical features. 12,13 Recently, endoscopic resection including endoscopic mucosal resection (EMR) or endoscopic submucosal dissection (ESD) has been established as a standard therapeutic M A N U S C R I P T A C C E P T E D ACCEPTED MANUSCRIPT method for differentiated intramucosal early gastric cancer (EGC) or even submucosal EGC confined to SM1 layer or ulcerative lesion < 3.0 cm in size, in the absence of lymphovascular invasion.…”

Section: Introductionmentioning

confidence: 99%

Endoscopic versus surgical resection of GI stromal tumors in the upper GI tract

Joo

Park

Kim

et al. 2016

Gastrointestinal Endoscopy

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Section: Introductionmentioning

confidence: 99%

Endoscopic versus surgical resection of GI stromal tumors in the upper GI tract

Joo

Park

Kim

et al. 2016

Gastrointestinal Endoscopy

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“…Recent studies have shown that endoscopic resection is safe and viable for patients with GISTs, even in tumors up to 5 cm in size [18]. In theory, endoscopic resection is a simple and feasible treatment for some tumors, but the risk of early tumor recurrence with incomplete resection is a major concern for the surgeon.…”

Section: Introductionmentioning

confidence: 99%

Endoscopic versus laparoscopic resection of gastric gastrointestinal stromal tumors: a multicenter study

et al. 2016

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Despite endoscopic resection has been performed to treat gastric gastrointestinal stromal tumor (GISTs). However, the safety and long-term outcomes remains controversial. This study aims to compare the safety and surgical outcomes of endoscopic versus laparoscopic resection of gastric GISTs. A total of 335 patients that were pathologically confirmed with gastric GISTs (tumor size ≤ 3.5 cm) were surgically treated with endoscopic resection (endoscopic group) or laparoscopic resection (laparoscopic group) in three institutions from March 1, 2011 to October 1 2014. These demographics, tumor characteristics, and outcomes were retrospectively analyzed for identification of outcomes and feasibility of endoscopic or laparoscopic resection. Of 335 patients, 262 and 73 patients underwent endoscopic and laparoscopic resection, respectively. The average tumor size was 1.33±0.78 cm in the endoscopic group and 1.97±0.93 cm in the laparoscopic group. The average operating time was 62.40±36.94 min in the endoscopic group and 112.81±55.69 cm in the laparoscopic group. Days of realimentation was 2.76±1.67 in the endoscopic group and 4.89±2.03 in the laparoscopic group. The average cost was $ 3246.01±1017.61 in the endoscopic group and $ 4884.81±1339.51 in the laparoscopic group. There was no postoperative mortality. Endoscopic resection for gastric GISTs is safe and feasible in tumors ≤ 3.5 cm. Because endoscopic resection showed good results with lower operating time, realimentation days, length of hospital stay and mean total cost, it is a minimally invasive and safe alternative approach which can achieve fast recovery and satisfactory outcomes for appropriately selected patients with gastric GISTs.

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“…Lipoma or lymphangioma sometimes can be inferred based on the exposed tissue after biopsy. According to studies on SMTs with the likelihood of malignancy, malignancy was observed in 3.7% of GISTs smaller than 2 cm [6], and metastasis was observed in 2% of carcinoids smaller than 1 cm [7]. For this reason, recent guidelines recommend histological diagnosis for SMTs larger than 2 cm (United States and Europe) or 1 cm (Japan).…”

Section: Diagnosis Of Esophageal Smtmentioning

confidence: 99%

Evaluation and Endoscopic Management of Esophageal Submucosal Tumor

Song

Cho

2017

Clin Endosc

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Submucosal tumors (SMTs) originate from tissues that constitute the submucosal layer and muscularis propria, and are covered by normal mucosa. Esophageal SMTs are rare, accounting for <1% of all esophageal tumors. However, the recent widespread use of endoscopy has led to a rapid increase in incidental detection of SMTs in Korea. Esophageal SMTs are benign in ≥90% of cases, but the possibility of malignancies such as gastrointestinal stromal tumor and malignant leiomyosarcoma still exists. Therefore, patients undergo resection in the presence of symptoms or the possibility of a malignant tumor. For resection of esophageal SMTs, surgical resection was the only option available in case of possible malignancy, but minimally invasive surgery by endoscopic resection is becoming more preferable to surgical resection with the development of endoscopic ultrasonography, endoscopic techniques, and other devices.

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Minimally Invasive Treatment of Gastric Gastrointestinal Stromal Tumors

Abstract: Laparoscopic surgery for gastric GIST is safe and feasible, even in large (>5 cm) tumors. Because endoscopic resection showed good results without recurrence, this approach can be useful in selected cases with a high operative risk or a need for preservation of organ function.

Cited by 56 publications

References 25 publications

Endoscopic versus surgical resection of GI stromal tumors in the upper GI tract

Endoscopic versus surgical resection of GI stromal tumors in the upper GI tract

Endoscopic versus laparoscopic resection of gastric gastrointestinal stromal tumors: a multicenter study

Evaluation and Endoscopic Management of Esophageal Submucosal Tumor

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