Minimal monitoring of ovarian hyperstimulation: a useful simplification of the clinical phase of in vitro fertilization treatment

Roest, Jan; Verhoeff, Arie; Heusden, Arne M. van; Zeilmaker, G. H.

doi:10.1016/s0015-0282(16)57791-7

Cited by 22 publications

(5 citation statements)

References 17 publications

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“…However, a considerable overlap of distribution of these values between OHSS and control populations has been found (Delvigne et al, 1991). Therefore, the value of intensive monitoring for prevention of OHSS has been debated (Tan, 1994;Roest et al, 1995b).…”

Section: Prevention Of Ohssmentioning

confidence: 99%

“…In several IVF programmes, monitoring of ovarian stimulation is carried out by transvaginal ultrasound examinations only (Tan, 1994;Wikland et al, 1994;Roest et al, 1995b). In these programmes the number of developing follicles is used as the criterion to cancel the cycles or proceed to oocyte retrieval.…”

Section: Prevention Of Ohssmentioning

confidence: 99%

“…In these programmes the number of developing follicles is used as the criterion to cancel the cycles or proceed to oocyte retrieval. The development of >30-35 follicles, corresponding with a serum oestradiol concentration of ∼6000 pg/ml (Asch et al, 1991), has been mentioned as the criterion for cancellation (Sher et al, 1993;Roest et al, 1995b).…”

Section: Prevention Of Ohssmentioning

confidence: 99%

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The incidence of major clinical complications in a Dutch transport IVF programme

Roest

Mous²,

Zeilmaker³

et al. 1996

Human Reproduction Update

122

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Four different major clinical complications were identified in a retrospective analysis of 2495 in-vitro fertilization (IVF) cycles resulting in oocyte retrieval. The severe form of ovarian hyperstimulation syndrome (OHSS) occurred in 18 patients, giving a prevalence for this complication of 0.7%. Seven (39%) of these 18 patients had previously been diagnosed as having polycystic ovaries. Eleven patients were admitted with moderate OHSS. Adnexal torsion was diagnosed in two patients. Ovariectomy was considered necessary in both cases. Complications of the transvaginal procedure occurred in seven cases (0.3%): one patient had an acute appendicitis with puncture holes in the appendix, six patients were admitted shortly after oocyte retrieval with a pelvic inflammatory disease. Of the 624 pregnancies obtained, 13 were ectopic, giving an ectopic pregnancy rate of 2.1%. It is concluded that serious clinical complications of IVF treatment are rare. However, patients should be counselled for the occurrence of serious procedure-related complications before entering an IVF programme.

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Section: Prevention Of Ohssmentioning

confidence: 99%

Section: Prevention Of Ohssmentioning

confidence: 99%

Section: Prevention Of Ohssmentioning

confidence: 99%

See 1 more Smart Citation

The incidence of major clinical complications in a Dutch transport IVF programme

Roest

Mous²,

Zeilmaker³

et al. 1996

Human Reproduction Update

122

View full text Add to dashboard Cite

show abstract

“…6,7 Cycles were cancelled before human chorionic gonadotrophin administration when fewer than three follicles had reached at least 14 mm after 12 days of ovarian stimulation. One to two cleavage-stage embryos were transferred to the uterus on day 2 or 3 after insemination under ultrasound guidance using an Edwards-Wallace embryo transfer catheter (Sims Portex Ltd, Hythe, Kent, UK).…”

Section: Treatment Protocolmentioning

confidence: 99%

“…All patients underwent controlled ovarian superovulation using the long downregulation protocol and either purified urinary FSH (Menopur, Ferring Pharmaceuticals Ltd, Berkshire, UK) or recombinant FSH (Gonal-F, Serono Ltd, Middlesex, UK, or Puregon, Organon Ltd, Cambridge, UK). 6,7 Cycles were cancelled before human chorionic gonadotrophin administration when fewer than three follicles had reached at least 14 mm after 12 days of ovarian stimulation. One to two cleavage-stage embryos were transferred to the uterus on day 2 or 3 after insemination under ultrasound guidance using an Edwards-Wallace embryo transfer catheter (Sims Portex Ltd, Hythe, Kent, UK).…”

Section: Treatment Protocolmentioning

confidence: 99%

Short communication: Validity of the in vitro fertilisation league tables: influence of patients’ characteristics

Johnson

El‐Toukhy

Sunkara

et al. 2007

BJOG

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We tested the hypothesis that restricting comparison of the live birth rate following in vitro fertilisation (IVF) treatment in those couples having their first IVF cycle in whom the female is under 35 years of age and has a normal follicle-stimulating hormone level would improve the validity of comparing IVF clinics' success rates. We analysed all cycles performed over a 2-year period in patients who fulfilled these criteria and divided the study population according to the referring primary care trusts: group A (n = 90) were referred from Lambeth, Southwark and Lewisham and group B (n = 134) were referred from Brent and Harrow. There was no significant difference between the two groups with regard to their IVF cycle characteristics. The two groups differed in their ethnicity, cause of infertility, prevalence of uterine fibroids and smoking and alcohol consumption habits. Group A had a significantly lower live birth rate (OR = 0.45, 95% CI 0.21-0.95, P = 0.02) compared with group B. This study confirms the impact of the non-IVF-related patient characteristics on treatment outcome and the poor validity of comparing IVF clinics' success rates based on the sparse data published by national IVF registries.

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Monitoring of stimulated cycles in assisted reproduction (IVF and ICSI)

Kwan¹,

Bhattacharya²,

McNeil³

et al. 2005

Cochrane Database of Systematic Reviews

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Minimal monitoring of ovarian hyperstimulation: a useful simplification of the clinical phase of in vitro fertilization treatment

Cited by 22 publications

References 17 publications

The incidence of major clinical complications in a Dutch transport IVF programme

The incidence of major clinical complications in a Dutch transport IVF programme

Short communication: Validity of the in vitro fertilisation league tables: influence of patients’ characteristics

Monitoring of stimulated cycles in assisted reproduction (IVF and ICSI)

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