Minimal difference between aerobic and progressive resistance exercise on metabolic profile and fitness in older adults with diabetes mellitus: a randomised trial

Ng, Cindy; Goh, Su-Yen; Malhotra, Rahul; Østbye, Truls; Tai, E. Shyong

doi:10.1016/s1836-9553(10)70021-7

Cited by 33 publications

(32 citation statements)

References 30 publications

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“…Overall, a total of 14 trials (16 reports) extracted from 9,477 articles met the eligibility requirements and were included for the present systematic review and meta-analysis [15][16][17][18][19][20][31][32][33][34][35][36][37][38][39][40]. One study was excluded since it was not described as randomised [41], and two trials provided no information on whether the AET was supervised [42,43].…”

Section: Resultsmentioning

confidence: 99%

“…Seven trials reported random sequence generation [16,31,32,[36][37][38][39], and only five trials reported allocation concealment [16,31,32,37,38]. None of the studies reported the blinding of volunteers towards the mode of intervention (ESM Fig.…”

Section: Risk Of Biasmentioning

confidence: 99%

“…1). Eight trials performed intention-to-treat analysis [15-17, 32, 35, 37-39], and six trials appear to have had adequate blinding of the outcome assessment [16,17,31,32,37,38]. High risk of bias was defined as fewer than four out of a maximum yield of six low risk of bias items using the risk of bias assessment tool from the Cochrane Collaboration (ESM Fig.…”

Section: Risk Of Biasmentioning

confidence: 99%

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Impact of different training modalities on glycaemic control and blood lipids in patients with type 2 diabetes: a systematic review and network meta-analysis

et al. 2014

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Aims/hypothesis This study aimed to systematically review randomised controlled trials comparing the effects of aerobic exercise training (AET), resistance training (RT) and combined training (CT) on glycaemic control and blood lipids in patients with type 2 diabetes mellitus. Methods Searches were performed in MEDLINE, EMBASE and the Cochrane Library. Inclusion criteria were: type 2 diabetes mellitus, adult, supervised training and a minimum intervention period of 8 weeks. Pooled effects were calculated by fixed/random effect pairwise and Bayesian fixed/random effects network meta-analyses. Results A total of 14 trials enrolling 915 participants were included. AET was more effective than RT in improving Conclusions/interpretation The present data suggest that CT might be the most efficacious exercise modality to improve glycaemic control and blood lipids. Interpretation with respect to clinical relevance is limited by the low quality of the studies included and the limited information on the clinically important outcomes or adverse effects of exercise.

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Section: Resultsmentioning

confidence: 99%

Section: Risk Of Biasmentioning

confidence: 99%

Section: Risk Of Biasmentioning

confidence: 99%

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Impact of different training modalities on glycaemic control and blood lipids in patients with type 2 diabetes: a systematic review and network meta-analysis

et al. 2014

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“…The study group was undergone 50 minutes of aerobic training with a target heart rate of 65% of their age-predicted maximum heart rate [14].…”

Section: Intensity and Duration Of Trainingmentioning

confidence: 99%

Effect of Aerobic Exercise on Serum Adiponectin and Serum Malondialdehyde (MDA) In Type 1 Diabetic Patients

El-Balshy¹

2017

EJPM

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Type 1 diabetes is fatal unless treated with insulin. Exercise interventions have been shown to be as efficient as the pharmaceutical agents to improve glycaemic control. The aim of the current study was to determine the effect of aerobic exercise on possible mechanisms controlling insulin resistance. Forty diabetic type 1 patients of both sexes (20 females and 20 males) were participated in the study. They were randomly divided into two equal groups. Study group comprised of 20 patients participated in a supervised moderate-intensity aerobic exercise program performed on bicycle ergometer for 50 minutes, 3 times per week, for 8 weeks, in addition to their medical treatment while the control group received only their medical treatment. The result showed that a significant decrease in insulin resistance in the Study group as compared to the control group. The mean values of adiponectin were significantly increased from 5.85±0.65 to 6.6±0.56 in the study group. The mean values of Malondialdehyde (MDA) and fasting glucose were significantly decreased from 7.2±0.98, 146.88±11.42 to 6.45±0.95, 133.87±11.99 respectively in the study group. It can be concluded that aerobic exercise has a positive effect on decreasing insulin resistance and hence decrease the incidence of diabetic complications.

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“…Singaporeans of Asian origin ( AT/RT,-0.3% /-0.4%) showed a slightly superior effect from RT compared to AT [92]. Similar to South Asians, Singaporeans also have a higher percentage of body fat for the same body mass index as Caucasians [93].…”

Section: The Independent Effects Of At and Rt In Glycemic Control -Efmentioning

confidence: 99%

The Effects of Supervised Aerobic and Resistance Exercise Training on Sri Lankan Adults with Type 2 Diabetes Mellitus - Sri Lanka Diabetes Aerobic and Resistance Training (SL-DART) Study

Ranasinghe¹

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Type 2 diabetes mellitus (T2DM) and the associated cardiovascular diseases (CVD) are contributing to rising global mortality [1]. South Asia is the home to almost one-fifth of the world's population [2]. South Asians are more prone to T2DM compared to other ethnicities [3].There is a high prevalence of diabetes (10-15%) in South Asian Sri Lankans [4] who are at a greater risk of CVD [5].Exercise is known to improve blood glucose, lipid profiles, blood pressure [6] and visceral adiposity [7] which are goals of diabetes management. Aerobic exercise training (AT) interventions have been studied widely; resistance exercises training (RT) interventions are becoming more prevalent. Some recommendations involve combining AT and RT interventions for the management and prevention of T2DM [9,10]. Currently there are no documented studies in Sri Lanka and limited studies conducted in South Asia, comparing the effects of AT with RT on people with T2DM on glycemic control, visceral adiposity (anthropometric), liver enzymes and, blood lipid profiles (biochemical).This thesis is novel because, to the best of my knowledge, there is no comparison of the effects of RT and AT on physiological and behavioural parameters in Sri Lankans. Studies tend to be conducted in White Caucasians who have a different body composition to South Asians. Secondly, the addition of a qualitative study to assess the barriers and facilitators for compliance and adherence to exercise has not been documented to date.The Randomized Controlled Trial (RCT) of the SL-DARTS recruited sedentary Sri Lankans (age 35-65 years) with T2DM (HbA1c 6.5-11.0%) from medical and diabetic clinics of the National Hospital of Sri Lanka (NHSL) and selected private sector clinics in the capital city, Colombo. They were randomized into aerobic training (AT), resistance training (RT) and control (CN) groups. Supervised progressive exercises were conducted 2 days/week for 3 months.Mean absolute changes in glycemic control (HbA1c) and percentage body fat were the primary outcomes. The change in glycaemia and insulin resistance (fasting blood sugar/FBS and fasting insulin/FI) lipid profile, liver enzymes, chronic inflammatory state, anthropometric measures (height, weight, body mass index/BMI, and waist / hip / mid-thigh / mid-arm circumferences), muscular strength, cardiovascular endurance, blood pressure, food preference, Quality of life, were secondary measures. All outcomes were measured within iii one week before the start date of the intervention (pre) and within one week after the intervention (post).A qualitative study using in-depth interviews was conducted to assess the experiences of the participants who completed the program. The themes discussed in the in-depth interviews were selected based on a critical literature review that was conducted on evidence-based cognitive behavioural approaches on exercise adoption and adherence. Percentage body fatChange in mean absolute body weight and BMI was minimal among groups. The absolute change in %BF in RT, AT and CN...

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Minimal difference between aerobic and progressive resistance exercise on metabolic profile and fitness in older adults with diabetes mellitus: a randomised trial

Abstract: NCT01000519.

Cited by 33 publications

References 30 publications

Impact of different training modalities on glycaemic control and blood lipids in patients with type 2 diabetes: a systematic review and network meta-analysis

Impact of different training modalities on glycaemic control and blood lipids in patients with type 2 diabetes: a systematic review and network meta-analysis

Effect of Aerobic Exercise on Serum Adiponectin and Serum Malondialdehyde (MDA) In Type 1 Diabetic Patients

The Effects of Supervised Aerobic and Resistance Exercise Training on Sri Lankan Adults with Type 2 Diabetes Mellitus - Sri Lanka Diabetes Aerobic and Resistance Training (SL-DART) Study

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