Impact of different training modalities on glycaemic control and blood lipids in patients with type 2 diabetes: a systematic review and network meta-analysis

Abstract

Aims/hypothesis This study aimed to systematically review randomised controlled trials comparing the effects of aerobic exercise training (AET), resistance training (RT) and combined training (CT) on glycaemic control and blood lipids in patients with type 2 diabetes mellitus. Methods Searches were performed in MEDLINE, EMBASE and the Cochrane Library. Inclusion criteria were: type 2 diabetes mellitus, adult, supervised training and a minimum intervention period of 8 weeks. Pooled effects were calculated by fixed/random effect pairwise and Bayesian fixed/random effects network meta-analyses. Results A total of 14 trials enrolling 915 participants were included. AET was more effective than RT in improving Conclusions/interpretation The present data suggest that CT might be the most efficacious exercise modality to improve glycaemic control and blood lipids. Interpretation with respect to clinical relevance is limited by the low quality of the studies included and the limited information on the clinically important outcomes or adverse effects of exercise.

Reciprocal changes of serum adispin and visfatin levels in patients with type 2 diabetes after an overnight fast

“…In type II diabetes, insulin resistance and obesity together cause mild to moderate hypertriglyceridemia and also cause reduction of HDL-C. Excessive production of TG-rich lipoproteins and its low clearance by lipoprotein lipase in diabetic patients may lead to hypertriglyceridemia (9). The aforementioned metabolic pattern was also confirmed in our study.…”

Exercise and the microbiota

“…1 The possibility that exercise or combined dietary change might enhance microbial diversity has immediate implications not limited to the elderly. The growing list of reported health benefits from exercise now includes: limitation of age-related cognitive impairment, 2 prevention of colon cancer 3 and the treatment of diabetes, 4 irritable bowel syndrome 5 and depression. 6 The microbiota and diet-microbehost immune and metabolic interactions have been implicated in the etiopathogenesis of all of these conditions.…”

Insulin use interferes with the effect of rehabilitation in Japanese stroke patients with diabetes mellitus: A propensity score-matched analysis

“…Insulin resistance is improved by appropriate exercise, [20][21] and it also improves motor function 8 and maintains cognitive function. 22 Therefore, we consider that it is necessary for stroke patients with type 2 diabetes, who are able to withdraw from insulin treatment, to undergo multifaceted treatment approaches, such as combination with biguanide [23][24] or DPP-4 inhibitors that do not increase body weight.…”