Minimal antimicrobial peptidic sequence from hemoglobin alpha-chain: KYR

Production of an antimicrobial peptide derived from slaughterhouse by-product and its potential application on meat as preservative

“…Two other fractions were identified and represent a133-141 peptide and a107-141 peptide. These two last peptides, according to Catiau et al (2011), were a137-141 precursors and showed the same kinetics compared to the purified bovine hemoglobin. In fact, a107-141 disappeared rapidly during the hydrolysis (DH = 10%) because it was an intermediate peptide.…”

“…In our case, the presence of tyrosine was estimated according to a137-141 sequence peptide (Catiau et al, 2011). The specific minima at 276 and 283.5 nm indicated this amino acid.…”

“…The first aim of this study was to confirm the great similarities between the purified bovine hemoglobin hydrolysis and the bovine cruor hydrolysis (Catiau et al, 2011). Different DH were investigated.…”

“…positive charges at pH 7 (Catiau et al, 2011), which has a large antibacterial spectrum, especially against pathogenic bacteria commonly responsible for food alteration, such as Escherichia coli, Salmonella enterica or Staphylococcus aureus (Borch & Arinder, 2002;Catiau et al, 2011). However, many studies have shown the enzymatic mechanism involved in the peptide generation for the purified bovine hemoglobin.…”

Effects of hydrolysis and digestion in vitro on the activity of bovine plasma hydrolysates as inhibitors of the angiotensin I converting enzyme

“…Animal blood produced during the sacrifice is one of these cases; it is additionally a valuable source of protein (Del Hoyo et al 2008). It has been found to produce various bioactive peptides, not only from its cellular fractioning, but also from the plasma (Lee and Song 2009;Liu et al 2009;Catiau et al 2011). To propose alternatives to use animal blood means a solution to an environmental perspective, since, in many cases, its large part is discharged in water-ways,, which is causes serious environment concerns.…”