Miniaturized sensors for the viscosity and density of liquids-performance and issues

Jakoby, Bernhard; Beigelbeck, Roman; Keplinger, Franz; Lucklum, Frieder; Niedermayer, A.O.; Reichel, Erwin K.; Riesch, Christian; Voglhuber-Brunnmaier, Thomas; Weiß, Bernhard

doi:10.1109/tuffc.2010.1386

Cited by 134 publications

(72 citation statements)

References 33 publications

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“…This can be downscaled by monitoring the dynamic response of magnetic nanoparticles to an oscillating magnetic field [20]. Several miniaturized sensors based on micromechanical devices [21] or piezoelastic vibrators [22] have also been developed to measure the viscosity down to dimensions of the order of 10 μm. The mechanical response of microfabricated cantilevers immersed in the fluid under study has also been used but is limited to gases [23] or liquids of low viscosities (<10 mPa s) because of the strong damping of the cantilever oscillation [24,25].…”

Section: Introductionmentioning

confidence: 99%

AFM study of hydrodynamics in boundary layers around micro- and nanofibers

et al. 2016

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The description of hydrodynamic interactions between a particle and the surrounding liquid, down to the nanometer scale, is of primary importance since confined liquids are ubiquitous in many natural and technological situations. In this paper we combine three nonconventional atomic force microscopes to study hydrodynamics around microand nanocylinders. These complementary methods allow the independent measurement of the added mass and friction terms over a large range of probe sizes, fluid viscosities, and solicitation conditions. A theoretical model based on an analytical description of the velocity field around the probe shows that the friction force depends on a unique parameter, the ratio of the probe radius to the thickness of the viscous boundary layer. We demonstrate that the whole range of experimental data can be gathered in a master curve, which is well reproduced by the model. This validates the use of these atomic force microscopy modes for a quantitative study of hydrodynamics and opens the way to the investigation of other sources of dissipation in simple and complex fluids down to the submicron scale.

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Section: Introductionmentioning

confidence: 99%

AFM study of hydrodynamics in boundary layers around micro- and nanofibers

et al. 2016

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“…For the manufactured rotor R c = 21.3 Ω and L c = 215 µH were obtained by fitting the parameters in the recorded frequency response from 100 Hz to 100 kHz. The output voltage was measured with a lock-in amplifier (with an input resistance of 10 MΩ) and reads V out (ω) = V M (ω) + (R c + j ω L c )I in (1) in complex notation where j = √ −1, ω is the angular frequency and the time dependence e j ω t is suppressed.…”

Section: Single Versus Double Coil Setupmentioning

confidence: 99%

“…Recently, we investigated various resonant sensors for liquid viscosity and mass density, see e.g., [1], which were particularly designed to be operated in the low kilohertz range. Amongst these devices, in-plane oscillating platelets, emitting mainly shear waves into the sample liquids, were investigated e.g., in [2,3] where millimeter sized metal platelets were used.…”

Section: Introductionmentioning

confidence: 99%

Electromagnetically driven torsional resonators for viscosity and mass density sensing applications

Heinisch¹,

Voglhuber-Brunnmaier²,

Reichel³

et al. 2015

Sensors and Actuators A: Physical

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In this contribution a conceptual study for torsional oscillators, which are electromagnetically driven and read out, is presented. The aim is to experimentally investigate the basic feasibility of a torsional resonator with application to viscosity and mass density sensing in liquids. Such a device is particularly interesting as cylindrical, torsional resonators for fluid sensing applications are hardly reported but unlike many other devices, yield pure shear wave excitation in the liquid. The design of first conceptual demonstrators for measurements in air as well as in liquids and their benefits and disadvantages are discussed in detail. A closed form as well as a reduced order model and measurement results obtained with first demonstrators are presented.

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“…According to Figure 67, the sensibility of the QCR prototype is around 3.2 Hz per 1mg/ml of sample concentration change. The linear behavior of the QCR response was confirmed [46,106,129,130].…”

Section: Sensibility and Limit Of Detection Of The Biosensormentioning

confidence: 61%

“…QCM-D technique has been used widely in different studies, i.e: cellular characterization [25,26,[91][92][93], protein detection [27,[94][95][96][97][98] and DNA detection [99][100][101][102][103][104], and viscosity analysis of different substances [37,46,67,100,[105][106][107][108].…”

Section: Impulse Excitation and Decay Methodsmentioning

confidence: 99%

Diseño y evaluación de un biosensor basado en resonadores de cristal de cuarzo (QCR) para caracterizar muestras biológicas relacionadas con enfermedades artríticas

Ahumada¹,

Armando²

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IVResumen de la tesis de Luis Armando Carvajal Ahumada, presentada como requisito parcial para la obtención del grado de DOCTOR en INGENIERÍA BIOMÉDICA. Madrid, 03 de Abril de 2017 DISEÑO Y EVALUACIÓN DE UN SENSOR BASADO EN RESONADORES DE CRISTAL DE CUARZO (QCR) PARA CARACTERIZAR MUESTRAS BIOLÓGICAS RELACIONADAS CON LA DIAGNOSIS DE ENFERMEDADES ARTRÍTICASResumen:Los resonadores de cristal de cuarzo son dispositivos ampliamente utilizados como biosensores debido a su alta sensibilidad ante fenómenos físico-químicos que ocurren en su superficie, a la reproducibilidad de las mediciones y por ser transductores fáciles de utilizar. Sauerbrey[1] fue el primero en demostrar que el resonador cristal de cuarzo puede ser utilizado como una microbalanza útil para caracterizar pequeñas deposiciones de masa en el electrodo del cristal. Sauerbrey demostró que, si se deposita una delgada capa de material rígido sobre el cristal de cuarzo, tanto el cristal como el material depositado vibrarán a la misma frecuencia y se generará un cambio en la frecuencia de resonancia inicial del cristal. Específicamente, la frecuencia de resonancia disminuye al aumentar la cantidad de masa depositada.El cristal de cuarzo también puede operar en medio fluidos. En este caso además del desplazamiento en frecuencia del cristal, se genera una pérdida significativa en el factor de calidad del resonador. Para fluidos Newtonianos (viscosidad constante), Kanazawa y Gordon[2] demostraron que el desplazamiento en frecuencia que sufre el resonador así como el cambio en el ancho de la curva de admitancia, depende de la densidad y la viscosidad del líquido. Este fenómeno permite utilizar los resonadores de cristal de cuarzo como pequeños viscosímetros siempre que se conozca la densidad del fluido a analizar.En el caso de deposición de fluidos viscoelásticos, la medición del cambio en la frecuencia de resonancia del cristal no es suficiente para obtener el valor de viscosidad del fluido. Por tanto, se requiere de la medición de una segunda variable (mitad del ancho de media banda -Γ) para obtener el valor correcto de la viscosidad del fluido depositado.[3] Para fluidos pseudoplásticos (viscosidad aparente dependiente de la velocidad de cizallamiento aplicada), se requiere de un modelo matemático que explique el comportamiento de la viscosidad del fluido a distintas velocidades de cizallamiento. En particular para el análisis de muestras con este comportamiento, se ha elegido el modelo Rouse ya que explica con suficiente detalle el comportamiento pseudoplástico y resulta simple de aplicar a las medidas experimentales.En este trabajo se propone el diseño de un biosensor basado en un resonador de cristal de cuarzo (QCR) para la caracterización de muestras biológicas que emulan el comportamiento del líquido sinovial.El líquido sinovial es una mezcla de plasma dializado y ácido hialurónico con comportamiento pseudoplástico. Su principal función es la de actuar como lubricante en las articulaciones V manteniendo al mínimo la fricción entre los huesos, especialment...

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Miniaturized sensors for the viscosity and density of liquids-performance and issues

Cited by 134 publications

References 33 publications

AFM study of hydrodynamics in boundary layers around micro- and nanofibers

AFM study of hydrodynamics in boundary layers around micro- and nanofibers

Electromagnetically driven torsional resonators for viscosity and mass density sensing applications

Diseño y evaluación de un biosensor basado en resonadores de cristal de cuarzo (QCR) para caracterizar muestras biológicas relacionadas con enfermedades artríticas

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