Miniaturized optoelectronic tweezers controlled by GaN micro-pixel light emitting diode arrays

Abstract

A novel, miniaturized optoelectronic tweezers (OET) system has been developed using a CMOS-controlled GaN micro-pixelated light emitting diode (LED) array as an integrated micro-light source. The micro-LED array offers spatio-temporal and intensity control of the emission pattern, enabling the creation of reconfigurable virtual electrodes to achieve OET. In order to analyse the mechanism responsible for particle manipulation in this OET system, the average particle velocity, electrical field and forces applied to the particles were characterized and simulated. The capability of this miniaturized OET system for manipulating and trapping multiple particles including polystyrene beads and live cells has been successfully demonstrated.

Active-Matrix GaN Micro Light-Emitting Diode Display With Unprecedented Brightness

“…Consequently, they are promising for applications requiring, or benefitting from, high intensity, e.g., displays in high brightness environments (sunlight), projection [8], optoelectronic tweezers [5], [6], or pumping of organic lasers [9]. A further consequence of high current density operation is a reduction of the carrier lifetime [10], making micro-LEDs attractive candidates for high-speed data transmission using visible light [11].…”

New optical, acoustic, and electrical diagnostics for the developing world

“…The generation of nonhomogenous electric fields is realised by gold electrodes on solid substrates, commonly. However, more dynamic and programmable DEP configurations are gained when using light induced dielectrophoresis 23,35 . Different light patterned electrode shapes are easily applied and reconfigurable when it is needed to design certain functions like focusing or trapping (Fig.5).…”

Dielectrophoretic behavior of a single cell when manipulated by optoelectronic tweezers: A study based on COMSOL ALE simulations

“…Instead of the amorphous silicon (a-Si:H), Yang et al [5,6] developed light-driven Ti-OET using an organic photoconductive material titanium oxide phthalocyanine to manipulate the HepG2 cell and picoliter gas bubble based on negative dielectrophoresis force. Moreover, lensintegrated LCD or COMS-controlled GaN LED as a micro-light source integrated into an OET device has been reported by Hwang [7] and Zarowna-Dabrowska et al [8]. Q3 Although many achievements has been made in various photoconductive materials and sources, the behavior of microparticle experienced the DEP force is not as well understood.…”

“…OET device structure and operating principle A typical OET chip, which is known as sandwich structure, consists of two ITO glass, aqueous solution and photoconductive thin film layers [8]. The aqueous layer containing cells or colloids is in the middle of between top and bottom ITO glass.…”