The nutritional quality and safety of oil extracted from noni (Morinda citrifolia) seeds was evaluated to determine its potential as a useful vegetable oil. The average oil content of noni seeds was found to be 124.9 g kg 1 . The mean linoleic acid content of crude noni seed oil was 59.4%. The average b-sitosterol, campesterol, stigmasterol, and a-tocopherol contents of noni seed oil were 4310, 2195, 2020, and 382 mg kg )1 , respectively. No evidence of acute oral toxicity was observed for noni seed or the oil at 5 g kg )1 b.w. and 10 mL kg )1 b.w., respectively. Noni seed oil was not gentoxic in the Salmonella typhimurium reverse mutation assay or the in vitro mammalian chromosomal aberration assay. These results indicate that noni seeds may be a useful new source of vegetable oil.