Mindfulness-based interventions for major depressive disorder: A comprehensive meta-analysis of randomized controlled trials

Self-disgust as a potential mechanism explaining the association between loneliness and depression

“…One way of achieving this goal is through mindfulness. In particular, studies have shown mindfulness-based interventions have been associated with reduced mental health problems, including depression, and with less ruminating thoughts and negative affect in both healthy and clinical populations (Chambers, Yee Lo, & Allen, 2008;van der Velden et al, 2015;Wang et al, 2018). Accordingly, neuroimaging research has shown that dispositional mindfulness was associated with greater regulation of negative affect through the prefrontal cortex (PFC), thus, suggesting that mindfulness can buffer the neuro-modulation of negative affect in the amygdala and enhance negative affect regulation through PFC activation (Creswell, Way, Eisenberger, & Lieberman, 2007).…”

Mechanisms of mindfulness: Rumination and self-compassion

“…In keeping with this, empirical evidence links training in mindfulness to reduced depressive symptoms. Although recently a critical meta-analysis concluded that mindfulness-based interventions only have weak effects on common psychiatric disorders (Hedman-Lagerlof, Hedman-Lagerlof, & Ost, 2018), several other meta-analyses and review studies conclude that mindfulness-based interventions such as MBSR and MBCT are effective in reducing depressive symptoms in non-clinical (Khoury, Sharma, Rush, & Fournier, 2015) and clinical samples (Goyal et al, 2014;Hofmann, Sawyer, Witt, & Oh, 2010;Strauss, Cavanagh, Oliver, & Pettman, 2014;Wang et al, 2018). For instance, Hoffman et al (2010) performed a meta-analysis based on 39 studies using clinical samples and found that mindfulness-based interventions were moderately effective in reducing depressive symptoms.…”

Mindfulness-based cognitive therapy for the treatment of current depressive symptoms: a meta-analysis

“…There has been a substantial increase in the number of studies published in the past several years examining the efficacy of MBCT among people who are currently experiencing depression or elevated symptoms of depression (see Table 1). While several meta-analyses have indicated that mindfulness-based interventions in generalincluding MBCT, mindfulness-based stress reduction (MBSR), and othersare effective at reducing depressive symptoms (see Goldberg et al, 2018;Goyal et al, 2014;Hedman-Lagerlöf, Hedman-Lagerlöf, & Öst, 2018;Khoury et al, 2013;Wang et al, 2018), to our knowledge no meta-analysis to date has examined the efficacy of MBCT specifically for patients with current depressive symptoms. However, such a meta-analysis is vital for establishing the efficacy of MBCT for this population (American Psychological Association, 2006).…”