Mindfulness- and acceptance-based interventions for psychosis: Our current understanding and a meta-analysis

Louise, Stephanie; Fitzpatrick, Molly; Strauss, Clara; Rossell, Susan L.; Thomas, Neil

doi:10.1016/j.schres.2017.05.023

Cited by 135 publications

(129 citation statements)

References 42 publications

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“…MBRP methods have been shown to decrease craving and depressive symptoms for comorbid substance use in depressive disorders (Zemestani & Ottaviani, ). A meta‐analysis of mindfulness‐based interventions for psychosis revealed that the intervention resulted in significantly reduced positive and negative psychotic symptoms when compared with TAU controls (Louise, Fitzpatrick, Strauss, Rossell, & Thomas, ). Nonetheless, mindfulness‐based intervention produced a nonsignificant difference in symptom scores when compared with active control groups.…”

Section: Treatment Of Mapmentioning

confidence: 99%

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Methamphetamine‐associated psychosis: Clinical presentation, biological basis, and treatment options

Chiang

Lombardi

et al. 2019

Human Psychopharmacology

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Introduction Methamphetamine associated psychosis (MAP) represents a mental disorder induced by chronic methamphetamine use in a subset of users. The prevalence of the disorder has increased in several countries in Europe and Asia where methamphetamine use has increased. MAP remains difficult to distinguish from primary psychiatric disorders, especially schizophrenia, creating complications in prescribing treatment plans to patients. Design This narrative review sought to summarize difficulties related to MAP diagnosis and highlight the need for a better treatment model. Current best practices are described and potential novel therapies and future research suggested. Results Results suggest that clear biological and clinical differences appear between patients presenting with MAP and schizophrenia and that there may exist distinct subgroups within MAP itself. MAP‐specific treatment studies have been few and have focused on the use of antipsychotic medication. Antipsychotic treatment has been shown to alleviate the psychotic symptoms of MAP but produce debilitating adverse effects and fail to adequately address methamphetamine use in patients. Conclusions Continued identification of subgroups within the heterogenous MAP population may lead to better diagnosis, treatment, and outcomes for patients. Psychosocial therapies should be explored in addressing the cooccurring substance use and psychosis in the treatment of MAP.

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Section: Treatment Of Mapmentioning

confidence: 99%

“…A meta-analysis of mindfulness-based interventions for psychosis revealed that the intervention resulted in significantly reduced positive and negative psychotic symptoms when compared with TAU controls (Louise, Fitzpatrick, Strauss, Rossell, & Thomas, 2018).…”

Section: Mindfulness-based Relapse Preventionmentioning

confidence: 99%

Methamphetamine‐associated psychosis: Clinical presentation, biological basis, and treatment options

Chiang

Lombardi

et al. 2019

Human Psychopharmacology

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“…There is a growing body of evidence from meta-analyses highlighting the significant effects of mindfulnessbased interventions on psychological well-being and physical health outcomes of individuals diagnosed with cancer (9), chronic pain (10), psychiatric disorders (11), as well as healthy individuals (12). In a recent meta-analysis of ten randomized controlled trials (RCTs) of mindfulness-and acceptance-based interventions in adults with psychotic disorders, group format mindfulness-based interventions showed larger therapeutic effects (Hedge's g = 0.46, 95% CI: 0.18-0.75) than individualbased Acceptance and Commitment Therapy (g = 0.08, 95% CI: −0.23 to 0.38) (13).…”

Section: Introductionmentioning

confidence: 99%

The Role of Five Facets of Mindfulness in a Mindfulness-Based Psychoeducation Intervention for People With Recent-Onset Psychosis on Mental and Psychosocial Health Outcomes

et al. 2020

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Objective: This study aimed to examine how five facets of mindfulness may be associated with the changes in psychotic patients' health outcomes after participating in a mindfulness-based psychoeducation group (MBPEG) program.Methods: Longitudinal follow-up data from two pragmatic randomized controlled trials of MBPEG for psychotic patients were used for this study. A total of 124 patients who completed the MBPEG program were included in this analysis. Patient outcomes (psychotic symptoms, functioning, insight into illness/treatment, subjective recovery) and five facets of mindfulness were assessed at baseline and six, 12 and 24 months post-intervention. Areas under the curve of individual outcomes in repeated-measures were computed using trapezoidal method, rescaled to the original possible range of the underlying variable and used for correlation and regression analyses.Results: All mean scores of the five facets increased across time and were significantly correlated with the improvements in all patient outcomes (p-values ranged from < 0.001 to <0.05), except "non-judging" facet and symptom severity. Regression analyses revealed that only "observing" and "acting with awareness" were significantly associated with positive changes across all outcomes (increase in adjusted R 2 ranged from 5.9% to 24.2%, p < 0.001).Conclusions: Two facets of mindfulness, "observing" and "acting with awareness," were related to positive outcomes of psychotic patients after participating in the MBPEG. More efforts in addressing these two facets of mindfulness can be considered to increase the efficacy of mindfulness-based interventions in psychosis.

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“…Previous reviews allude to the complexity of psychological therapies as a potential obstacle to engagement for patients with significant psychotic symptoms [6]. This study found that the majority of in-patients in a Psychiatric Rehabilitation setting (roughly two thirds) are prepared to try mindfulness practice groups, and this compares very favourably with other therapeutic activities on offer on wards from psychologists and other members of the multidisciplinary team.…”

Section: Discussionmentioning

confidence: 84%

The introduction of mindfulness groups to a Psychiatric Rehabilitation in-patient setting: a feasibility study

Millar

Tip

Lennon

et al. 2020

Preprint

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Background Patients within Psychiatric Rehabilitation services have multiple, complex and enduring difficulties, and are frequently described as ‘treatment resistant’. This group have diagnoses of major mental health conditions, most commonly schizophrenia, often alongside a history of complex trauma, co-morbid alcohol/ substance misuse, and cognitive impairment. There is no known effective medical treatment other than Clozapine in this patient group, however, there is preliminary evidence that mindfulness can help individuals with psychosis by improving their ability to cope with stressful internal experiences. This study aimed to determine if mindfulness practice groups are an acceptable therapeutic intervention in an in-patient rehabilitation setting. The study also aimed to monitor the well-being of those who participated. Methods Mindfulness practice groups were offered three times weekly on a 15-bedded rehabilitation ward in a psychiatric hospital over five months, and weekly in a second ward over an 18 month period. The sessions were delivered by Clinical Psychologists in accordance with adaptations for a psychosis population. Attendance data were gathered on both wards and additional measures of well-being were collected on one ward. Qualitative interviews were conducted with a sample of patients, group facilitators, and staff, to provide supplementary information about the acceptability of the intervention. Results In both wards around two thirds (65%, 67%) of in-patients attended at least one group and smaller proportion (around a third) went on to attend regularly. There was no discernible impact on well-being using the Warwick-Edinburgh well-being scale. Qualitative interviews suggested a number of benefits to individuals attending as well as the potential for groups to enhance the therapeutic culture within wards. Conclusions Clinical guidelines suggest that all patients with a diagnosis of psychosis should have access to psychological therapies, but delivering psychological therapy within an in-patient rehabilitation setting can be challenging. This preliminary feasibility study suggests that mindfulness practice groups are an acceptable intervention, and that further research to look at the effectiveness of mindfulness for symptoms of treatment-resistant psychosis is both possible and merited.

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Mindfulness- and acceptance-based interventions for psychosis: Our current understanding and a meta-analysis

Cited by 135 publications

References 42 publications

Methamphetamine‐associated psychosis: Clinical presentation, biological basis, and treatment options

Methamphetamine‐associated psychosis: Clinical presentation, biological basis, and treatment options

The Role of Five Facets of Mindfulness in a Mindfulness-Based Psychoeducation Intervention for People With Recent-Onset Psychosis on Mental and Psychosocial Health Outcomes

The introduction of mindfulness groups to a Psychiatric Rehabilitation in-patient setting: a feasibility study

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