Milky mushroom: A healthy nutritious diet

The Current Status, Bioactivity, Food, and Pharmaceutical Approaches of Calocybe indica: A Review

“…In a study by Mishra et al (2014) [ 52 ], natural foods containing antioxidants were used to reduce oxidative damage, herein the methanolic extract of caps of Calocybe indica at a concentration of 1 mg/mL showed a total antioxidant activity of 45.31 ± 2.16 µM, whereas the stipes exhibited 25.78 ± 1.22 µM antioxidant activity at the same concentration proving that the caps of Calocybe indica have more antioxidant potential than that of stipes. According to several findings, Ghosh (2022) [ 15 ] concluded that the toxicological screening found a complete absence of anatoxin and phallotoxin. Herein, experimental rats feeding on mushroom water extract did not produce any toxic effect, whereas this could be consumed as a safe healthy food, indicating its potential to be developed as a non-toxic antimicrobial agent.…”

“…The urge for functional foods from natural resources over synthetic ingredients is rising with age in the industry and foods could be available as dietary supplements, pharmafoods, phytochemicals, and myco-chemicals [ 15 ]. Mushrooms are used in a variety of ways, including as meals, dietary supplements, and medicines known as “mushroom pharmaceuticals” [ 63 ].…”

“…The DPPH radical scavenging capability of Calocybe indica was found to be greatly reduced during the microwaving and boiling processes; however, stir-frying increased both the activity and phenolic content (970.03 mg gallic acid equivalent/L of extract) and it has been suggested that stir-frying as a cooking method might improve the beneficial characteristics of Calocybe indica . It has been concluded that milky mushrooms might be employed as an additional nutrient in food items since it is a novel functional food element for a healthy lifestyle [ 15 ].…”

“…Pleuran, lentinan, schizophyllan, β-glucans, mannans, chitin, hemicellulose, galactans, and xylans polysaccharides are regarded as probiotic properties of Calocybe indica polysaccharides [ 14 ]. Individuals are discovering healthier functional food alternatives that are rich in metabolic goodness and provide protection against disease, and mushrooms perfectly fit into the group of functional foods [ 15 ]. Several scientific investigations have highlighted different pharmaceutical properties of mushrooms such as antioxidant, antimicrobial, anticancer, and immunomodulatory activity on various extracts of milky mushroom [ 16 ].…”

“…Mushrooms are improving in the field of complementary and alternative medicine (CAM) as a functional food due to their ability to modulate humoral and innate immunity as well as revitalize the weakened immune system. From Calocybe indica , proteins and glucans were isolated and both of these compounds showed immunostimulatory effects and also stimulated the activity of natural killer cells which kill cancerous cells directly [ 15 ]. These remarkable functional, physiochemical, and techno-functional properties of Calocybe indica mushroom make them a promising ingredient in the food and pharmaceutical industry.…”