Milia en plaque

Abstract

Milia plaque is an unusual and rare variant of milia. We now report a Chinese man with numerous milia within an erythematous plaque of the upper and lower eyelids; histology confirmed the diagnosis and showed pericystic inflammation. All but one of the previous 10 reported cases affected the ear or adjacent sites, and to our knowledge, this is the first reported case of milia en plaque affecting the eyelids.

Bilateral Milia En Plaque of the Eyelids: Long Eyelashes and Unibrow—Case Report and Review of Literature

“…Only four other cases (Table 1). [1][2][3][4] Three cases showed unilateral involvement. 1,3,4 A predilection for women has been reported (3:1) but no familial occurrence.…”

Milia em placa

“…1,[4][5][6] Evidence shows that the primary forms of milia originate in the hair follicle infundibulum, whereas the secondary forms may originate in various annexal structures such as the sweat ducts, sebaceous glands and hair follicles. 1,7 Clinical differential diagnosis is made between MEP and secondary milia with plaques and other conditions that may simulate MEP. Cases of secondary milia en plaque have been described in patients with lupus erythematosus, pseudoxanthoma elasticum, lichen planus follicularis tumidus and lichenoid eruption, contact dermatitis, folliculotropic mycosis fungoides with cysts and comedones, follicular mucinosis and in patients in use of cyclosporine following organ transplantation, although doubt remains with respect to this last group.…”

“…7 MEP may regress spontaneously; however, it generally remains unchanged if untreated. 4 Although benign, the lesion's appearance may be distressful to the patient, who may request treatment for this reason.…”

“…This type of inflammation appears to be characteristic of the disease, since it has been reported in various cases of MEP published in the literature. 1,3,7,11 In some of the reported cases, there was infiltration of lymphocytes in the dermis adjacent to the cyst or confined to the perivascular space. 4,5 The presence of eosinophils and vellus hair inside the cysts has been described, but was not found in the present case.…”

Bilateral Extensive Periorbital Milia en Plaque Treated with Electrodesiccation

“…The first case of MEP involving eyelids was reported by Wong and Goh in 1998. 15 Stefanidou and colleagues reported a new case of periorbital MEP in 2002 and reviewed 20 cases of MEP reported until then. 16 These included MEP occurring in the preauricular area (three patients), in the inner canthus area (three patients), on the upper and lower eyelids (two patients), and in the submandibular region (one patient).…”