Mild‐to‐moderate intensity exercise improves cardiac autonomic drive in type 2 diabetes

Abstract

Aims/IntroductionThe aim of the present study was to determine the effect of moderate aerobic exercise on cardiac autonomic function in type 2 diabetic patients.Materials and MethodsHeart rate variability of 20 patients with type 2 diabetes was assessed. Resting electrocardiogram for the heart rate variability analysis at spontaneous respiration was recorded for 5 min in the supine position before and after 6 months of supervised aerobic training given three times per week.ResultsIn time domain measures, the square root of the mean of the sum of the squares of differences between adjacent R-R intervals (RMSSD; 29.7 [26–34.5] vs 46.4 [29.8–52.2] ms, P = 0.023) and the percentage of consecutive RR intervals that differ by more than 50 ms (pNN50; 10.7 [5.5–12.7] vs 26.1 [6.6–37.2]%, P = 0.025] were significantly increased after exercise. In frequency domain measures, low frequency (62.4 [59.1–79.2] vs 37 [31.3–43.3] nu, P = 0.003) and low frequency/high frequency (1.67 [1.44–3.8] vs 0.58 [0.46–0.59]%, P = 0.009) were significantly decreased, whereas high frequency (95 [67–149] vs 229 [98–427] ms2, P = 0.006) and high frequency (37.6 [20.8–40.9] vs 63 [56.7–68.7] normalized units, P = 0.003) were significantly increased after exercise. In a Poincaré plot, standard deviation perpendicular to the line of the Poincaré plot (SD1; 21.3 [18.5–24.8]–33.1 [21.5–37.2] ms, P = 0.027) was significantly increased after exercise.ConclusionsThese data suggest that three times per week moderate intensity aerobic exercise for 6 months improves cardiac rhythm regulation as measured by heart rate variability in type 2 diabetic patients.

Impact of a 12-week aerobic exercise training program on anthropometric and metabolic parameters of a group of type 2 diabetes Cameroonian women aged ≥50 years

“…In fact, increase in VO 2 Max is closely related to increase in metabolic activities of the cells (12), and therefore to reduced blood levels of nutrients such as glucose and lipids. It is also associated with improvement of the cardiac autonomic function in T2DM patients (18). Furthermore, an increased aerobic capacity is the reflect of a potential good productive capacity at work (17).…”

Cardiac autonomic dysfunction in survivors of childhood acute lymphoblastic leukemia: The St. Jude Lifetime Cohort Study

“…demonstrated a more rapid HRR (12.6 vs 2.6 bpm, P < 0.005; exercise group vs control group) in 12 patients with heart failure who participated in an eight‐week supervised exercise program consisting of walking and stationary cycling compared with those ( N = 12) who did not participate in a formal exercise intervention. Data from other populations, including individuals with diabetes mellitus, 34 chronic heart failure, 35 and polycystic ovarian syndrome, 36 have reported improved cardiac autonomic function after completion of an exercise intervention.…”

“…This is important, as CAD may be one of the few late effects of childhood cancer treatment that is modifiable. Existing literature demonstrates that exercise intervention improves HRR and cardiac autonomic function 34‐36,55,56 . Among survivors, improving the ability of the autonomic nervous system to respond to exercise may make it more comfortable to participate in physical activity, improve exercise tolerance, and help mitigate increased morbidity and mortality associated with a sedentary lifestyle.…”

Порівняльна Характеристика Впливу Омега-3 Поліненасичених Жирних Кислот, Статинів Та Їх Комбінування На Показники Ліпідного Спектра Крові, Судинно-Тромбоцитарного Гомеостазу І Варіативності Ритму Серця У Хворих На Цукровий Діабет 2-Го Типу З кардіоваскуля

“…Низькі показники ВРС корелюють із ризиком раптової смерті навіть більшою мірою, ніж фракція викиду, категорія шлуночкових аритмій та фізична толерантність [7]. Зниження ВРС у хворих на ЦД-2 є маркером КАН і розглядається як предиктор ССЗ та смертності [8]. Повідомляється, що субклінічна стадія КАН характеризується вираженими змінами ВРС, а саме зниженням тонусу парасимпатичної ланки вегетативної нервової системи, що обумовлює відносне підвищення тонусу симпатичної ланки та зростання симпато-парасимпатичного індексу (LF/HF).…”