Mild hydration of didecyldimethylammonium chloride modified DNA by 1H-nuclear magnetic resonance and by sorption isotherm

Abstract

Low-temperature 1H NMR spectroscopic study of hydration properties of a hybrid system based on nanosilica, DNA and doxorubicin in the presence of C60 fullerene Low Temp. Phys. 40, 239 (2014); 10.1063/1.4866907 Nuclear magnetic relaxation induced by exchange-mediated orientational randomization: Longitudinal relaxation dispersion for a dipole-coupled spin-1/2 pair Progress in C 13 and H 1 solid-state nuclear magnetic resonance for paramagnetic systems under very fast magic angle spinningThe gaseous phase hydration of deoxyribonucleic acid and didecyldimethylammonium chloride (C 19 H 42 ClN) complexes (DNA-DDCA) was observed using hydration kinetics, sorption isotherm, and high power nuclear magnetic resonance. Three bound water fractions were distinguished: (i) a very tightly bound water not removed by incubation over silica gel, (ii) a tightly bound water saturating with the hydration time t h 1 ¼ (0.59 6 0.04) h, and a loosely bound water fraction, (iii) with the hydration time t h 2 ¼ (20.9 6 1.3) h. Proton free induction decay was decomposed into the signal associated with the solid matrix of DNA-DDCA complex (T Ã 2S % 30 ls) and two liquid signal components coming from tightly bound (T Ã 2L 1 % 100 ls) and from loosely bound water fraction (T Ã 2L 2 % 1000 ls).

Temperature evolution of hydration shells in solid DNA didecyldimethylammonium chloride complex studied by 1H NMR spectroscopy

“…In our previous papers [15,30] we presented a hydration kinetics of a model complex of DNA and didecyldimethyl-ammonium chloride (DDCA), studied by 1 H NMR spectroscopy. In the NMR signal we identified three component distinctly different in molecular mobility, manifesting as different values of relaxation times T 2 ⁄ (spin-spin), and T 1 (spin-lattice).…”

Hydration properties of selected DNA-lipid complexes

“…W dalszym tekście będą stosowane terminy "woda bardzo ściśle związana", "woda ściśle związana" oraz "woda luźno związana", używane przez autorów niniejszej pracy kon sekwentnie we wszystkich pracach poświęconych hydra tacji materiałów biologicznych, np. [23].…”

Changes in Optical Parameters of SiO2:TiO2 Films Obtained by Sol-Gel Method Observed as a Result of Thermal Treatment

“…Direct methods routinely used to study hydration, such as sorption isotherm [ 12 ] or 1H NMR [ 13 ], are useless when thin layers are the subject of study because of insufficient sample volume (and mass). This limitation does not apply to ellipsometry, and this technique was used in the reported research to investigate phenomena occurring in SiO 2 :TiO 2 as a result of thermal treatment.…”