Migration of Antimicrobial Silver from Composites of Polylactide with Silver Zeolites

Fernández, Avelina; Soriano, Eva; Hernández‐Muñoz, Pilar; Gavara, Rafael

doi:10.1111/j.1750-3841.2010.01549.x

Cited by 118 publications

(83 citation statements)

References 21 publications

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“…Ag + ions are ion-exchanged out of the zeolite powder into media and are sufficient to cause bacterial cell death in both E coli and Staphylococcus aureus. 9,10 In the case of Ag + -zeolite, the release of Ag + into solution is primarily determined by the ionic strength of the medium, because this is an ion-exchange process and is media-dependent. Recently, there has also been a report of AgNP in zeolite powders and their activity towards Gram-positive and Gramnegative bacteria.…”

Section: Introductionmentioning

confidence: 99%

Silver nanoparticles embedded in zeolite membranes: release of silver ions and mechanism of antibacterial action

Nagy

Harrison²,

Sabbani³

et al. 2011

IJN

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Background The focus of this study is on the antibacterial properties of silver nanoparticles embedded within a zeolite membrane (AgNP-ZM). Methods and Results These membranes were effective in killing Escherichia coli and were bacteriostatic against methicillin-resistant Staphylococcus aureus. E. coli suspended in Luria Bertani (LB) broth and isolated from physical contact with the membrane were also killed. Elemental analysis indicated slow release of Ag + from the AgNP-ZM into the LB broth. The E. coli killing efficiency of AgNP-ZM was found to decrease with repeated use, and this was correlated with decreased release of silver ions with each use of the support. Gene expression microarrays revealed upregulation of several antioxidant genes as well as genes coding for metal transport, metal reduction, and ATPase pumps in response to silver ions released from AgNP-ZM. Gene expression of iron transporters was reduced, and increased expression of ferrochelatase was observed. In addition, upregulation of multiple antibiotic resistance genes was demonstrated. The expression levels of multicopper oxidase, glutaredoxin, and thioredoxin decreased with each support use, reflecting the lower amounts of Ag + released from the membrane. The antibacterial mechanism of AgNP-ZM is proposed to be related to the exhaustion of antioxidant capacity. Conclusion These results indicate that AgNP-ZM provide a novel matrix for gradual release of Ag + .

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Section: Introductionmentioning

confidence: 99%

Silver nanoparticles embedded in zeolite membranes: release of silver ions and mechanism of antibacterial action

Nagy

Harrison²,

Sabbani³

et al. 2011

IJN

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show abstract

“…Silver-containing zeolite compounds received approval of Food and Drug Administration (FDA) for being used as food contact surfaces (Joerger, 2007). Silver-zeolites have already been incorporated into polymeric films yielding antimicrobial properties (Kamisoglu et al, 2008;Zampino et al, 2008;Fernández et al, 2010). Polymer composites of plasticized poly(vinylchloride) pellets with silver zeolites demonstrated activity against S. epidermidis and E. coli (Zampino et al, 2008), while polyurethane composites with silver zeolites showed antimicrobial action against E. coli (Kamisoglu et al, 2008) and polylactid acidpolylactide (PLA)/silver zeolite composites also presented activity against S. aureus and E. coli, with silver being effectively released from the films .…”

Section: B Amentioning

confidence: 99%

Antimicrobial Biomimetics

María¹,

Barbassa²,

Melo³

2011

Biomimetic Based Applications

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“…Moreover, the European Food Safety Agency (EFSA) stated that in order to attain antibacterial effects, migrated ions ought to be in the range of the legal limit of 50 lg Ag ? /kg food (Fernandez et al 2010). Thus, our material could be safe for food packaging because its release is lower than legal limit.…”

Section: Morphology Analysis Of Nanofibersmentioning

confidence: 99%

Polylactic acid (PLA)/Silver-NP/VitaminE bionanocomposite electrospun nanofibers with antibacterial and antioxidant activity

Munteanu

Aytaç

Pricope³

et al. 2014

J Nanopart Res

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The antibacterial property of silver nanoparticles (Ag-NPs) and the antioxidant activity of Vitamin E have been combined by incorporation of these two active components within polylactic acid (PLA) nanofibers via electrospinning (PLA/Ag-NP/VitaminE nanofibers). The morphological and structural characterizations of PLA/Ag-NP/VitaminE nanofibers were performed by Scanning Electron Microscopy (SEM), Transmission Electron Microscopy and X-ray diffraction. The average fiber diameter was 140 ± 60 nm, and the size of the Ag-NP was 2.7 ± 1.5 nm. PLA/Ag-NP/VitaminE nanofibers inhibited growth of Escherichia coli, Listeria monocytogenes and Salmonella typhymurium up to 100 %. The amount of released Ag ions from the nanofibers immersed in aqueous solution was determined by Inductively Coupled Plasma Mass Spectrometry, and it has been observed that the release of Ag ions was kept approximately constant after 10 days of immersion. The antioxidant activity of PLA/Ag-NP/VitaminE nanofibers was evaluated according to DPPH (2,2-diphenyl-1-picrylhydrazyl) method and determined as 94 %. The results of the tests on fresh apple and apple juice indicated that the PLA/Ag/VitaminE nanofiber membrane actively reduced the polyphenol oxidase activity. The multifunctional electrospun PLA nanofibers incorporating Ag-NP and Vitamin E may be quite applicable in food packaging due to the extremely large surface area of nanofibers along with antibacterial and antioxidant activities. These materials could find application in food industry as a potential preservative packaging for fruits and juices.

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Migration of Antimicrobial Silver from Composites of Polylactide with Silver Zeolites

Cited by 118 publications

References 21 publications

Silver nanoparticles embedded in zeolite membranes: release of silver ions and mechanism of antibacterial action

Silver nanoparticles embedded in zeolite membranes: release of silver ions and mechanism of antibacterial action

Antimicrobial Biomimetics

Polylactic acid (PLA)/Silver-NP/VitaminE bionanocomposite electrospun nanofibers with antibacterial and antioxidant activity

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