Migraine epidemiology and comorbidities in Southern Israel: a clinical database study in a universal health coverage setting

Peles, Ido; Asla, Mohnnad; Abayev, Mariya; Gordon, Michal; Novack, Victor; Ribalov, Rinat; Lengil, Tamar; Maor, Ron; Elizur, Mayera; Ifergane, Gal

doi:10.1186/s10194-022-01513-w

Cited by 4 publications

(3 citation statements)

References 27 publications

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“…These results corroborated with the Japanese study, where allergies accounted for the most common 49.4% of comorbidities [23]. In our cohort, depression was reported by 21.3% participants, which coincides with American observations (23.2%), but is higher than in the Japanese Waliszewska-Prosół et al The Journal of Headache and Pain (2023) 24:40 (15.4%) and Israeli (3%) population [23,34]. A detailed discussion of comorbidities in the Polish Migraine study will be discussed in a separate report.…”

Section: Discussionsupporting

confidence: 92%

Migraine symptoms, healthcare resources utilization and disease burden in a large Polish migraine cohort

et al. 2023

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Background The Migraine in Poland study is the first large scale nationwide cross-sectional online survey of symptoms, approaches to management, treatment patterns, quality of life, and sociodemographic characteristics of the Polish migraine patients’ cohort, conducted from August 2021 to June 2022. Methods A cross-sectional online survey was designed based on the American Migraine Prevalence and Prevention (AMPP) Study. Participants were recruited through broad advertisement through various channels. The survey included questions allowing for the diagnosis of migraine without aura (MwoA) based on the third edition of the International Classification of Headache Disorders (ICHD-3). Moreover, the questionnaire assessed sociodemographic and headache features, comorbidities, consultation rates with medical professionals, as well as the use of abortive or preventive treatment, including non-pharmacological methods, psychological symptoms and the burden of migraine. Results A structured online questionnaire was submitted by 3225 respondents aged 13 to 80 (mean age 38.9, 87.1% women). In this group 1679 (52.7%) of participants fulfilled ICHD-3 diagnostic criteria for MwoA, which was in most cases (88.3%) confirmed by a medical professional in the past. In this group the average number of monthly headache days was 4.7, while 47.8% of participants had at least 4 migraine days per month. Mean Migraine Disability Assessment score was 42.65 (median 32). Among MwoA respondents, 1571 (93.6%) had consulted their headache with a medical professional in the past – mostly neurologists (n = 1450 (83.4%) and primary care physicians (n = 1393 (82.9%). In the MwoA cohort, 1553 (92.5%) of participants declared the current use of some form of treatment, although only 193 (11.5%) respondents were currently on preventive medications. The most prevalent comorbidities included: chronic rhinitis (37.1%), allergies (35.9%) and low blood pressure (26.9%). Anxiety (20.4%) and depression (21.3%) were highly prevalent among participants. Conclusions People with migraine in Poland face similar difficulties as their peers in other countries. Despite relatively high access to neurologist consultations and good diagnosis accuracy, migraine still poses diagnostic and therapeutic difficulties. In this context, migraine undertreatment in Polish population must be underlined, especially in context of high disease burden.

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Section: Discussionsupporting

confidence: 92%

Migraine symptoms, healthcare resources utilization and disease burden in a large Polish migraine cohort

et al. 2023

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“…A matched control group was identi ed as well. The methodology, as well as the characteristics of the patients, is described in detail in a previous paper (15).…”

Section: The Negev Migraine Cohort (Nmc)mentioning

confidence: 99%

Migraine and Work – Beyond Absenteeism Migraine Severity, Occupational Burnout and Commuting Time – A Cohort Study

Peles,

Sharvit,

Zlotnik

et al. 2024

Preprint

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Background Migraine, a prevalent cause of disability, significantly impacts work productivity, particularly within the prime age range of 25 to 55 years. This cohort study delves into the complex relationship between migraine severity, occupational burnout, and commuting time. Going beyond traditional indicators of work impairment like absenteeism and presenteeism, our research explores additional work-related consequences of migraine, such as decisions regarding workplace proximity and reduced engagement at work. By investigating the connections between migraine severity, psychiatric comorbidities, commuting durations, and occupational burnout, our study aims to offer a more comprehensive understanding of the broader impacts of migraine on employment. Methods Focus groups of migraine patients highlighted burnout and commuting as significant migraine-related concerns. A subset of participants from the Negev Migraine Cohort, including both migraine sufferers and control subjects, were systematically enlisted to complete our study questionnaire. The questionnaire covered demographic information, health status, and employment details. Additionally, levels of depression, anxiety, and stress were assessed using the DASS-21 scale, while migraine severity was gauged by migraine frequency and the MIDAS score. Occupational burnout was measured using the MBI-GS scale. Statistical analysis, incorporating descriptive, univariate, and multivariate methods, was employed to identify correlations and adjust for pertinent variables. Results A total of 675 migraine patients and 232 control subjects participated in the study. Migraine patients, who were predominantly female and younger compared to the controls, exhibited higher rates of depression, anxiety, and stress. However, there was no significant difference in self-rated health between the two groups. Despite similar employment rates, migraine patients tended to work longer hours and expressed a preference for remote work. Notably, migraine patients reported higher levels of occupational burnout than controls, with a notable correlation to psychological distress. Among migraine patients, men reported experiencing higher levels of burnout. After controlling for depression, anxiety, and stress, migraine severity was found to be correlated with occupational burnout. Although commuting times were similar for both groups, higher migraine severity was associated with shorter commuting times, particularly among men. Conclusions The study reveals that migraine severity serves as an independent predictor of occupational burnout, even when considering psychiatric comorbidities associated with migraine. Interestingly, men with migraine report elevated levels of burnout, contrary to conventional gender expectations. This may be attributed to migraine-related cognitive disturbances intensifying cognitive overload at work, thereby increasing the likelihood of occupational burnout. Interestingly, men with migraine report elevated levels of burnout, contrary to previous reports. Moreover, a higher severity of migraine is linked to shorter commuting times, indicating a tendency for migraine patients to avoid travel, which in turn limits their employment options. The preference among migraine patients for remote work aligns with this observation. Although the study may be limited by potential sample bias, its findings underscore the necessity for workplace adjustments to allow migraine sufferers to achieve maximal occupational capacity.

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“…Migraine is a debilitating and common disease affecting millions worldwide [ 1 ]. The Headache Classification Committee of the International Headache Society (IHS) defines migraine as recurrent episodes of headache often accompanied by nausea, vomiting, photophobia, and phonophobia [ 2 ].…”

Section: Introductionmentioning

confidence: 99%

Prevalence of migraine in Iran: a systematic review and meta-analysis

et al. 2023

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Background Migraine headaches affect all ages, from childhood to old age. Migraine attacks cause significant changes in the living conditions of the sick person, including a decrease in personal, social, and occupational performance. This study was conducted to determine the prevalence of migraine in Iran through a systematic review and meta-analysis. Method In this systematic review and meta-analysis study, the studies associated with the prevalence of migraine using the keywords: migraine, prevalence, and Iran its equivalents in international databases PubMed, Web of Science, Scopus, Science direct, and Iranian internal information databases, including SID and MagIran, was searched without limit until November 2022. Comprehensive Meta-Analysis software (Version 2) was used to analyze the data. Due to the high number of studies reviewed in this systematic review, the Begg and Mazumdar test was used at a significance level of 0.1, and the corresponding Funnel plot was used to check publication bias. Also, the I2 test was used to check the heterogeneity in this study. Results 22 records were included in the final analysis. The prevalence of migraine in the general population of Iran was 15.1% (confidence interval 95%: 10.7–20.9), and in this population, the prevalence of migraine was higher in women than in men. The prevalence of migraine based on The International Classification of Headache Disorders (ICHD) 2 criteria was reportedly 16.4% (95% CI: 10.8–24.1), and with ICHD3 criteria, this value was reported as 17.1% (95% CI: 7.7–33.6). Based on a survey of 4571 children, the prevalence of migraine was reported to be 5.2% (95% CI: 1.3–18.7). Also, the prevalence of migraine in adolescents was calculated based on eight studies (n = 8820). Accordingly, 11.2% (95% CI: 5.8–20.4) of adolescents have migraines. Meanwhile, the prevalence of migraine in boys was 8.2% (95% CI: 4.8–13.7), and in girls was 8% (95% CI: 6.2–12.7). Conclusion As a result, the prevalence of migraine in Iran, based on population-based studies, was reported as 15.1%. The result showed a higher prevalence of migraine in the general population than in children and adolescents. It was also found that the prevalence of migraine in women is higher than in men.

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Migraine epidemiology and comorbidities in Southern Israel: a clinical database study in a universal health coverage setting

Cited by 4 publications

References 27 publications

Migraine symptoms, healthcare resources utilization and disease burden in a large Polish migraine cohort

Migraine symptoms, healthcare resources utilization and disease burden in a large Polish migraine cohort

Migraine and Work – Beyond Absenteeism Migraine Severity, Occupational Burnout and Commuting Time – A Cohort Study

Prevalence of migraine in Iran: a systematic review and meta-analysis

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