Mielitis longitudinalmente extensa y virus del Zika, reto diagnóstico: a propósito de un caso en hospital de Colombia 2016

Palacios, Eduardo; Clavijo-Prado, Carlos; Ruiz, Adrián Alonso; Antun, A. Arias; Durán, Enric

doi:10.1016/j.nrl.2016.08.006

Cited by 15 publications

(9 citation statements)

References 7 publications

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“…Neurological manifestations are among the most serious complications of Zika virus infection, including transverse myelitis [1,7,8,9,10,11]. This severity is related to the incapacities generated by the disease, becoming a social problem with a high cost for the public health system.…”

Section: Discussionmentioning

confidence: 99%

“…The zika virus belongs to the family flaviviridae and it is transmitted by the arthropod Aedes aegypt [1]. Zika virus infection is one of the most important emerging viral diseases in the last decade worldwide, due to several debilitating clinical manifestations, sequelae and perinatal involvement with severe cases of congenital Zika syndrome.…”

Section: Introductionmentioning

confidence: 99%

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Transverse myelitis associated with Zika virus infection: a Case Report

Casagrande¹,

Sousa

Machado

et al. 2018

int arch med

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Background: The zika virus belongs to the family flaviviridae, and is transmitted by the arthropod Aedes aegypt. Its major importance is related to the several debilitating neurological manifestations associated with it, such as transverse myelitis. Case:The authors report a case of transverse myelitis in a patient with a previous diagnosis of Zika virus infection. After the image exams and serology, the diagnosis was confirmed and treatment with prednisone was performed with an unsatisfactory clinical outcome. Conclusion:Brazil is the country of greatest concern worldwide due to the thousands of Zika cases with associated neurological complications, causing sequels and physical disabilities. However, cases worldwide have increased substantially.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Transverse myelitis associated with Zika virus infection: a Case Report

Casagrande¹,

Sousa

Machado

et al. 2018

int arch med

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“…Spinal cord involvement in ZIKV can vary, and previous reports have described different forms of involvement. 11,17,27,28 Clinical symptoms are diverse and depend on the location and extension of the lesion. We can speculate that ZIKV might also specifically affect the anterior horns of the spinal cord (Fig 3), leading to a motor neuron syndrome, similar to the West Nile virus.…”

Section: Neurologic Disorders Associated With Zika Virus Infection Inmentioning

confidence: 99%

Neuroimaging Findings of Zika Virus–Associated Neurologic Complications in Adults

Cruz

Nascimento

Lopes

et al. 2018

AJNR Am J Neuroradiol

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When the first suspected cases of neurologic disorders associated with the Zika virus were noticed in Brazil in late 2015, several studies had been conducted to understand the pathophysiology of the disease and its associated complications. In addition to its well-established association with microcephaly in neonates, the Zika virus infection has also been suggested to trigger other severe neurologic complications in adults, such as Guillain-Barré syndrome, radiculomyelitis, and meningoencephalitis. Hence, the Zika virus should be deemed a global threat that can cause devastating neurologic complications among individuals in all age ranges. The aim of this review was to further describe neuroimaging findings of Zika virus infection and associated neurologic complications found in adults.

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“…Patients typically present with variable motor, sensory, and autonomic dysfunction depending on the location and extent of cord involvement. An important and distinctive finding in the physical examination is the presence of a sensory level [11,12].…”

Section: Zikv-related Acute Transverse Myelitis (Atm)mentioning

confidence: 99%

“…The signal changes are best seen on fluid-sensitive pulse sequences [e.g., T2-weighted image, short-tau inversion recovery (STIR), and fluid-attenuated inversion recovery (FLAIR)] as hyperintense areas, and the spinal cord may be enlarged due to edema. Variable degrees and patterns of post-contrast enhancement may be present in the involved segments of the spinal cord [11,12].…”

Section: Zikv-related Acute Transverse Myelitis (Atm)mentioning

confidence: 99%

Neuroimaging findings of postnatally acquired Zika virus infection: a pictorial essay

et al. 2017

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Zika virus (ZIKV) is a mosquito-borne arbovirus from the Flaviviridae family, first discovered in 1947. There has been no report of severe complications caused by this virus in humans until recently. However, it is confirmed now that prenatally acquired ZIKV infection may cause severe congenital brain abnormalities in the infected fetuses. In addition, there has been an increasing number of reports during recent years about the causal relationship between postnatally acquired ZIKV infection and severe neurologic complications (mostly immune-mediated ones). Hence, ZIKV should not be considered as benign as it was initially thought, but it might be seen as a serious global threat to human health that may severely affect not only fetuses. In this pictorial essay, we aim to describe and illustrate the currently recognized spectrum of neuroimaging findings in postnatally acquired ZIKV infection. Although neurologic complications do not frequently occur in postnatal ZIKV infection, it is important to be aware of them because they may cause high morbidity and mortality in the affected patients. In addition to clinical and laboratory findings, neuroimaging may help in the diagnostic work-up to make the correct diagnosis, determine the extent of the disease, and follow the clinical course.

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Mielitis longitudinalmente extensa y virus del Zika, reto diagnóstico: a propósito de un caso en hospital de Colombia 2016

Cited by 15 publications

References 7 publications

Transverse myelitis associated with Zika virus infection: a Case Report

Transverse myelitis associated with Zika virus infection: a Case Report

Neuroimaging Findings of Zika Virus–Associated Neurologic Complications in Adults

Neuroimaging findings of postnatally acquired Zika virus infection: a pictorial essay

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