Midline Posterior Fossa Teratoma. Case Report.

Desai, Ketan; Nadkarni, Trimurti; Muzumdar, Dattatraya; Goel, Atul

doi:10.2176/nmc.41.94

Cited by 19 publications

(9 citation statements)

References 13 publications

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“…Encephalic teratomas are rare and account for 2 to 5% of infant teratomas and 0.3 to 0.6% of all ventricular tumors. Teratomas may occur at any age, but with a higher incidence rate in younger patients (1). In addition, the incidence rate in males is marginally higher than that in females.…”

Section: Introductionmentioning

confidence: 99%

Immature teratoma of the posterior cranial fossa in a 4-month-old infant: A case report

Gao

Zheng

2013

Oncology Letters

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The present study analyzed a case of immature teratoma in the posterior cranial fossa of an infant and compared the clinical data with the associated literature. Ventricular drainage was initially performed upon the patient’s admission to the hospital. Following adequate pre-operative preparations, the tumor in the posterior cranial fossa was resected on the third day. No significant neurological function deficiency was observed following the surgery and no recurrence was noted within an 18-month follow-up period. In such cases, treatment should be conducted in a stepwise manner, with the hydrocephalus relieved first, followed by complete tumor resection subsequent to full preparation. Post-operative chemotherapy was not performed by conventional means as the infant was too weak, therefore, periodic reviews and long-term follow-up were required.

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Section: Introductionmentioning

confidence: 99%

Immature teratoma of the posterior cranial fossa in a 4-month-old infant: A case report

Gao

Zheng

2013

Oncology Letters

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“…They occur primarily in children, and congenital examples are well-recognized (1,8,9). Teratomas account for 2% of intracranial tumors in patients younger than 15 years of age (3,10).…”

Section: Discussionmentioning

confidence: 99%

Mature Intracranial Teratoma

Dimov¹,

Tasić²,

Stojanović³

et al. 2013

Acta Facultatis Medicae Naissensis

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ACTA FACULTATIS MEDICAE NAISSENSISUDC: 616.831-006Teratomas constitute a group of nongerminomatous germ cell tumors that are composed of an admixture of different tissue types representative of ectoderm, endoderm and mesoderm. Intracranial teratomas are rare, comprising approximately 0.5% of all intracranial tumors. They preferentially involve the midline structures, and occur primarily in children.We presented an unusual case of mature intracranial teratoma with extracranial extension in a 24-year-old man who complained of headache, nausea and vomiting. The intracranial expansive lesion was localized in the left frontotemporobasal region extending into the ipsilateral orbit. The patient underwent total resection of the tumor. No adjuvant treatment was given. On gross examination, the resected tumor was lobulated, containing heterogeneous solid and cystic components. Histologic investigation revealed the presence of various fully differentiated tissues representative of the three germ cell layers, including adipose tissue, cartilage, bone, striated muscle bundles, brain tissue, respiratory epithelium and glandular structures. The diagnosis of mature teratoma was established. Follow-up at four years did not show any evidence of recurrence.The presented case is an unusual example of mature teratoma with regards to the age of the patient and, especially, to the location of the tumor, both intraand extracranially. It is critical to recognize this rare entity by extensive sampling to rule out the presence of immature elements which may constitute only a minor part of the tumor.

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“…Thus, infratentorial teratomas are rare entities. Histopathologically, teratomas are categorized as mature or immature [6]. Immature teratomas are associated with poor prognosis, due to the malignant behavior and presentation at a young age [6].…”

Section: Introductionmentioning

confidence: 99%

Infratentorial immature teratoma of congenital origin can be associated with a 20-year survival outcome: a case report and review of literature

2019

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BackgroundCongenital intracranial tumors are very rare and account for less than 2% of all childhood brain tumors. Teratomas constitute about one third to one half of these, predominantly located midline in the supratentorial region. Posterior fossa location rarely occurs and, based on the cases reported in the literature, commonly has a poor prognosis.Case presentationA newborn female, diagnosed prenatally with hydrocephalus, is presented at birth with increasing head circumference and Parinaud’s syndrome. Magnetic resonance imaging scans demonstrated a huge posterior fossa tumor with obstructive hydrocephalus. At surgery, through a suboccipital craniotomy, complete excision was achieved of a histological-proven immature teratoma. The infant received adjuvant chemotherapy for 1 year. She had normal neurological development and remained tumor-free through her 20-year follow-up.ConclusionThe authors report this rare case of congenital posterior fossa teratoma with long-term outcome, and the literature is reviewed.

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Midline Posterior Fossa Teratoma. Case Report.

Abstract: A 20-day-old female neonate presented with an immature teratoma in the midline posterior fossa. The tumor was totally removed but the patient died of pneumonia. Teratoma is a rare tumor, but very difficult to treat as the patients tend to be young, and the outcome is very poor.

Cited by 19 publications

References 13 publications

Immature teratoma of the posterior cranial fossa in a 4-month-old infant: A case report

Immature teratoma of the posterior cranial fossa in a 4-month-old infant: A case report

Mature Intracranial Teratoma

Infratentorial immature teratoma of congenital origin can be associated with a 20-year survival outcome: a case report and review of literature

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