Middle ear tuberculosis: Diagnostic criteria

Jesić, S; Stošić, Svetlana; Milenković, Branislava; Nešić, Vladimir; Dudvarski, Zoran; Jotić, Ana; Slijepčević, Nikola

doi:10.2298/sarh0908346j

Cited by 21 publications

(22 citation statements)

References 6 publications

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“…In our study we did not encounter any complications, which contradicts a study done by Jesic S who reported that otogenic complications were more in tuberculous otitis media as compared to cholesteatoma [12]. In our series, detection rate of Mycobacteria by molecular genetic methods was about 4.5 times higher compared to direct staining and 2.5 times higher compared to concentration techniques.…”

Section: Discussioncontrasting

confidence: 94%

Tuberculous Otitis Media—A Rare Entity or a Missed Diagnosis

Deenadayal¹,

Kumar²,

Bommakanti³

et al. 2016

IJOHNS

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Section: Discussioncontrasting

confidence: 94%

Tuberculous Otitis Media—A Rare Entity or a Missed Diagnosis

Deenadayal¹,

Kumar²,

Bommakanti³

et al. 2016

IJOHNS

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“…Skin testing with purified protein derivative (Mantoux test) is not a very reliable test, in an anergic patient or if he is on steroid medication, and especially in endemic areas. 27,28 Chest X-ray showed evidence of active pulmonary tuberculosis in 66.67% (8 cases). Results from other reports include a positivity to the extent of 42.86% (Plester et al, 1980), 51.61% (Yaniv E, 1987) and 93.02% (Singh B, 1991).…”

Section: Discussionmentioning

confidence: 99%

“…30 Polymerase chain reaction (PCR), of the ear discharge can aid in analysis of treatment results and identifying bacilli in aural discharge. 28 The diagnosis of TOM was established by biopsy and histopathological study of the granulation tissues obtained on outdoor basis in 3 cases (all 3 being recurrence cases). With the institution of ATT the granulations resolved and ear became dry.…”

Section: Discussionmentioning

confidence: 99%

Tubercular otitis media: an under diagnosed entity

Maheshwari

Panigrahi

2016

Int J Otorhinolaryngol Head Neck Surg

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Background: Tubercular otitis media (TOM) is a well described rare entity in literature. Its characteristic diagnostic delay leads to severe irreversible complications. Diagnosis is much more difficult when it co-exists with aural cholesteatoma. Its Actual incidence is thought to be much more, than what is reported in literature. This study was carried out to establish TOM as an under diagnosed entity and to study its various presentations. Methods: A prospective study was performed in 617 cases (both recurrence and new) of chronic otitis media who gave a fully informed consent, for being investigated for a probable diagnosis of TOM, based on history and clinical findings. Histopathological examination of the granulation tissue retrieved during biopsy/mastoid exploration surgery and mycobacterial culture of the aural discharge was performed in all cases. A final diagnosis was made with either of tests being reported as positive for mycobacterium tuberculosis infection. All confirmed cases were treated with a 6 month course of anti-tubercular therapy. Results: Diagnosis of TOM was confirmed in 12 cases. M:F ratio was 1:1.4. Cholesteatoma was found to co-exist in 4 cases (33.33%). A positive histopathology report was obtained in 11 cases (91.67%) while the mycobacterial culture yielded growth in 3 cases (25%) only. Canal wall down mastoidectomy was performed in 9 cases. In all cases, a follow-up with a 6 months course of anti-tubercular therapy gave satisfactory healing with no complications. Conclusions: The incidence of TOM, a potentially dangerous entity is on a rise. Role of surgery is crucial in procuring tissue for histopathological and bacteriological examination. It is a curable disease if diagnosed in time with early institution of anti-tubercular therapy.

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“…При КТ височных костей на ранних стадиях ГВ наблюдают снижение пневматизации барабанной полости и клеток сосцевидного отростка без остеодеструкции, при генерализации -более характерна деструкция клеток сосцевидного отростка. На КТ височных костей при ТСО наблюдают чаще деструктивные изменения на фоне пневматического строения сосцевидных отростков [8,15,[18][19][20]. При ТСО у 0-41,6% больных развивается ранний токсический периферический парез лицевого нерва [1] (в нашем исследовании -у 27,3% пациентов).…”

Section: результаты и обсуждениеunclassified

Atypical inflammation of the middle ear

Garov¹,

Kryukov²,

Zelenkova³

et al. 2017

Vestn. otorinolaringol.

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The objective of the present study was to characterize the patients presenting with atypical inflammation of the middle ear and consider the currently available methods for their examination. A total of 20 patients at the age from 16 to 66 years were admitted to the Department of Ear Microsurgery during the period from 2008 and 2016 for the treatment of atypical inflammation of the middle ear. Eleven of them (18 ears) were found to have tuberculous lesions (TL) of the middle ear while the remaining 9 patients (11 ears) suffered giant cell vasculitis (GCV). All the patients underwent the general clinical and otorhinolaryngological examination, computed tomography of the temporal bones and the thoracic cavity organs, cytological, bacteriological, pathomorphological, and molecular-genetic studies including PCR diagnostics, rheumatological tests, as well as counseling by a phthisiotherapist and rheumatologist. The primary localization of TL in the middle ear was documented in 6 patients including its association with lung lesions in 5 cases. The clinical picture of the disease in 5 patients was that of smoldering exudative pathology and in 6 ones was accompanied by suppurative perforative otitis media. According to the laboratory analyses, bacteriological diagnostics proved efficient in 9% of the patients, pathomorphological and cytological diagnostics in 18% and 27.3% of the cases respectively while the effectiveness of PCR diagnostics was estimated at 55%. The diagnosis in individual patients was established within the period from 1 month to 1.5 years after they first sought medical advice in connection with complaints of the ear disease. Tuberculosis of the middle ear began to develop as exudative middle otitis that acquired the form of bilateral pathology in 4 patients. Three patients had a concomitant pulmonary disease. In 4 patuents, the diagnois of middle ear tuberculosis was established based on the presence of the specific antibodies and in 5 ones based on the results of the pathomorphological study. All the studies were carried out in duplicate. The period between the beginning of the disease and the establishment of the definitive diagnosis varied from 1 month to 1 year.

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Middle ear tuberculosis: Diagnostic criteria

Cited by 21 publications

References 6 publications

Tuberculous Otitis Media—A Rare Entity or a Missed Diagnosis

Tuberculous Otitis Media—A Rare Entity or a Missed Diagnosis

Tubercular otitis media: an under diagnosed entity

Atypical inflammation of the middle ear

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