Middle-aged female sexual dysfunction and multimorbidity

Valadares, Ana Lúcia Ribeiro; Lui-Filho, Jeffrey Frederico; Costa-Paiva, Lúcia; Pinto‐Neto, Aarão Mendes

doi:10.1097/gme.0000000000000533

Cited by 17 publications

(10 citation statements)

References 26 publications

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“…Most of them (63 studies) were cross-sectional design, and seven 21,23,39,43,54,57,60 had a longitudinal design, from which we used data from the baseline assessment. Only 5 out of 70 22,47,75,76,80 studies focused solely on subgroups of either men or women. The number of diseases included in eligible studies ranged from 4 to 40 (with hypertension, diabetes, arthritis and stroke being four most frequent conditions).…”

Section: Resultsmentioning

confidence: 99%

Prevalence of multimorbidity in community settings: A systematic review and meta-analysis of observational studies

et al. 2019

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Background: With ageing world populations, multimorbidity (presence of two or more chronic diseases in the same individual) becomes a major concern in public health. Although multimorbidity is associated with age, its prevalence varies. This systematic review aimed to summarise and meta-analyse the prevalence of multimorbidity in high, low- and middle-income countries (HICs and LMICs). Methods: Studies were identified by searching electronic databases (Medline, Embase, PsycINFO, Global Health, Web of Science and Cochrane Library). The term ‘multimorbidity’ and its various spellings were used, alongside ‘prevalence’ or ‘epidemiology’. Quality assessment employed the Newcastle-Ottawa scale. Overall and stratified analyses according to multimorbidity operational definitions, HICs/LMICs status, gender and age were performed. A random-effects model for meta-analysis was used. Results: Seventy community-based studies (conducted in 18 HICs and 31 LMICs) were included in the final sample. Sample sizes ranged from 264 to 162,464. The overall pooled prevalence of multimorbidity was 33.1% (95% confidence interval (CI): 30.0–36.3%). There was a considerable difference in the pooled estimates between HICs and LMICs, with prevalence being 37.9% (95% CI: 32.5–43.4%) and 29.7% (26.4–33.0%), respectively. Heterogeneity across studies was high for both overall and stratified analyses ( I 2 > 99%). A sensitivity analysis showed that none of the reviewed studies skewed the overall pooled estimates. Conclusion: A large proportion of the global population, especially those aged 65+, is affected by multimorbidity. To allow accurate estimations of disease burden, and effective disease management and resources distribution, a standardised operationalisation of multimorbidity is needed.

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Section: Resultsmentioning

confidence: 99%

Prevalence of multimorbidity in community settings: A systematic review and meta-analysis of observational studies

et al. 2019

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“…As shown in table 1, Brazil contributes with a total of 20 data points [15][16][17][18][19][20][21][22][23][24][25][26][27][28][29][30][31][32][33][34] ; Mexico with 4 data points 23 35-37 ; Peru with 3 data points 36 38 39 ; Colombia with 2 data points 23 40 ; and Argentina, 41 Cuba, 36 Dominican Republic, 36 El Salvador, 23 Jamaica, 23 Panama, 23 Puerto Rico 36 and Venezuela 36 with 1 data point each. On the other hand, only 16 studies analysed a nationally representative sample (table 1).…”

Section: General Characteristics Of Selected Studiesmentioning

confidence: 99%

Multimorbidity in Latin America and the Caribbean: a systematic review and meta-analysis

et al. 2021

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ObjectiveTo estimate the pooled prevalence of multimorbidity (≥2 non-communicable diseases in the same individual) among adults of the general population of Latin American and the Caribbean (LAC).DesignSystematic review and meta-analysis.Data sourcesMEDLINE, Embase, Global Health, Scopus and LILACS up to 1 July 2020.Eligibility criteria for selecting studiesThe outcome was the prevalence of multimorbidity. Reports were selected whether they enrolled adult individuals (age ≥18 years) from the general population.Data extraction and synthesisReviewers extracted relevant data and assessed risk of bias independently. A random-effects meta-analysis was conducted to report pooled prevalence estimates of multimorbidity; pooled estimates by pre-specified subgroups (eg, national studies) were also pursued.ResultsFrom 5830 results, we selected 28 reports, mostly from Brazil and 16 were based on a nationally representative sample. From the 28 selected reports, 26 were further included in the meta-analysis revealing a pooled multimorbidity prevalence of 43% (95% CI: 35% to 51%; I2: 99.9%). When only reports with a nationally representative sample were combined, the pooled prevalence was 37% (95% CI: 27% to 47%; I2: 99.9%). When the ascertainment of multimorbidity was based on self-reports alone, the pooled prevalence was 40% (95% CI: 31% to 48%; I2: 99.9%); this raised to 52% (95% CI: 33% to 70%; I2: 99.9%) for reports including self-reported and objective diagnosis.ConclusionsOur results complement and advance those from global efforts by incorporating much more reports from LAC. We revealed a larger presence of multimorbidity in LAC than previously reported.PROSPERO registration numberCRD42020196177.

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“…8 The prevalence of sexual dysfunction in women in menopause is high, ranging from 35.9 to 67% among women from different Brazilian locations. [9][10][11][12] Urogenital changes resulting from hypoestrogenism have the potential to reverberate in postmenopausal sexual function, 13 changing the domains of desire, excitement, and orgasm, and impacting interpersonal functioning and quality of life. [14][15][16] Estrogen interferes with the female sexual function by having a central action in the hypothalamus and preoptic area that leads to a positive influence on motivation, mood, and sexual desire.…”

Section: Introductionmentioning

confidence: 99%

Sexual Function and Associated Factors in Postmenopausal Women

Trento

Madeiro

Rufino

2021

Rev Bras Ginecol Obstet

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Objective To assess the sexual function and associated factors in postmenopausal women. Methods This a descriptive, cross-sectional study with 380 women aged 40 to 65 years, users of public health services in 2019. Questionnaires were applied on demographic characteristics, on climacteric symptoms (menopause rating scale) and on sexual function (sexual quotient, female version). Bivariate and multiple analyses by logistic regression were performed, with adjusted odds ratios (ORad) and 95% confidence intervals (95%CIs). Results More than half (243/64%) of the participating women were at risk of sexual dysfunction, with lower scores in the domains of sexual desire and interest, comfort, orgasm, and satisfaction. Women with a partner (ORad 2.07; 95%CI 1.03–4.17) and those who reported sleep problems (ORad 2.72; 95%CI 1.77–4.19), depressed mood (ORad 2.03; 95%CI 1.32–3.10), sexual complaints (ORad 8.16; 95%CI 5.06–13.15), and vaginal dryness (ORad 3.44; 95%CI 2.22–5.32) showed greater chance of sexual dysfunction. Conclusion There was a high prevalence of sexual dysfunction, with the influence of conjugality and climacteric symptoms on sexual function.

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Middle-aged female sexual dysfunction and multimorbidity

Cited by 17 publications

References 26 publications

Prevalence of multimorbidity in community settings: A systematic review and meta-analysis of observational studies

Prevalence of multimorbidity in community settings: A systematic review and meta-analysis of observational studies

Multimorbidity in Latin America and the Caribbean: a systematic review and meta-analysis

Sexual Function and Associated Factors in Postmenopausal Women

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