Mid-ventricle Takotsubo in a Patient with Goodpasture Syndrome

Abstract

Takotsubo syndrome (TTS) is characterized by transient, regional systolic dysfunction of the left ventricle, often mimicking acute coronary syndrome. Atypical variants of this syndrome with mid-ventricular, basal, and focal wall motion patterns are increasingly diagnosed and show different clinical features compared to typical TTS. Even though TTS was generally considered a benign condition, continuous and strict monitoring is necessary to diagnose potentially life-threating complications. This is the first case report, to our knowledge, of atypical TTS in a patient with Goodpasture syndrome triggered by acute kidney injury (AKI).

A Unique Case of Goodpasture’s Syndrome-Induced Cardiorenal Syndrome

“…GPS is rare and there is scarce literature on subsequent cardiac manifestations [ 12 , 22 , 23 ], especially after failed GPS treatment. Moreover, to our knowledge, this is the first case to demonstrate anti-GBM-positive GPS concurrently with dilated cardiomyopathy.…”