2021
DOI: 10.1186/s12872-021-02213-0
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Mid-term outcomes of off-pump versus on-pump coronary artery bypass graft surgery; statistical challenges in comparison

Abstract: Background Despite several studies comparing off- and on-pump coronary artery bypass grafting (CABG), the effectiveness and outcomes of off-pump CABG still remain uncertain. Methods In this registry-based study, we assessed 8163 patients who underwent isolated CABG between 2014 and 2016. Propensity score matching (PSM), inverse probability of weighting (IPW) and covariate adjustment were performed to correct for and minimize selection bias. … Show more

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Cited by 11 publications
(7 citation statements)
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“…The high proportion of male patients may have reduced the effect of gender on the statistical results. Mid-term survival and cardiovascular adverse event trends for on-pump CABG and off-pump CABG have been suggested to be comparable [ 12 , 13 ]. But on-pump CABG and off-pump CABG may differ in serum cytokine and chemokine levels and oxidative stress status, which may affect postoperative outcomes [ 14 , 15 ].…”
Section: Discussionmentioning
confidence: 99%
“…The high proportion of male patients may have reduced the effect of gender on the statistical results. Mid-term survival and cardiovascular adverse event trends for on-pump CABG and off-pump CABG have been suggested to be comparable [ 12 , 13 ]. But on-pump CABG and off-pump CABG may differ in serum cytokine and chemokine levels and oxidative stress status, which may affect postoperative outcomes [ 14 , 15 ].…”
Section: Discussionmentioning
confidence: 99%
“…However, mid-term results were comparable in both groups. In current study, we implanted IPW, which uses the whole data set and by reweighting individuals, increases the weight of those with unexpected exposures; ultimately, IPW creates a pseudo-population in which the covariates are balanced excellent between studied groups [17]. Management of patients with CAD and low EF remains a challenge; however, CABG seems to be a good surgical option in terms of survival and quality of life [18].…”
Section: Discussionmentioning
confidence: 99%
“…This registry-based prospective study was performed at Tehran Heart Center (THC) [ 18 ], evaluating CABG patients between January 2006 and December 2016. The study was performed according to the Declaration of Helsinki.…”
Section: Methodsmentioning
confidence: 99%